Colistin and carbapenem antibiotics are the last line of human beings, but perhaps not for long.
The chain of E. coli resistant to the last two antibiotics (last resort antibiotics) was found in the United States. And this is definitely an extremely bad news.
This bacterium was found in the urine of a man who had been treated at New Jersey Hospital two years ago. This is one of the test samples carried out for this study in 2016, which is part of a large bacterial analysis at this hospital.
To treat difficult-to-treat infections, two antibiotics Carbapenem and Colistin have been included in the treatment process. They are considered the two biggest shots and are also the last defensive measure that people sometimes have no longer any medicine to work.
In recent months, the mcr-1 gene resistant to Colistin has been found in E. coli bacteria in 30 countries, including patients isolated in China and now has a patient found in America.
Similarly, blaNDM-5 gene has also been resistant to Carbapenem antibiotics . In 2012, the Centers for Disease Control and Prevention discovered that 4% of US hospitals have coli-resistant bacteria.
Researchers and health experts fear that combining these two dangerous genes into one type of bacteria will produce a type of virus that has no cure. And that fear has come true, when people discovered that these types of bacteria appear in Germany, Venezuela and China, have not seen its appearance in American soil until today.
Fortunately, although this type of E. carbapenem is resistant to both Colistin and Carbapenem, it is still attacked by other antibiotics. And so far, there is no evidence that this bacterium is spread through tested patients.
But finding the gene mcr-1 and blaNDM-5 in the same host is very ominous. Each of these genes carries one capable of moving between different types of bacteria. Finding them in the US means being able to find them elsewhere is very high.
"The bad news is that the test urine sample has been around for two years, obviously, there are still drug-resistant bacteria that we haven't discovered yet, " said Professor Barry Kreiswirth at Rutgers University in one of the talks. Press Conference.
Emerging bacteria are caused by people using too many antibiotics for themselves and the livestock industry. In his warning posted in the mBio magazine, Professor Kreiswirth and his colleagues have said that their discovery is a warning for other scientists to embark on the search and research. How to kill this antibiotic resistant bacterium.