The cause of infertility has been identified

British scientists have identified that the enzyme SGK1 is the cause of infertility and miscarriage in women.

>>>New findings bring hope to infertility

Scientists from College London have taken samples from the uterine lining of more than 100 women. Results for every 6 women who have one person are difficult to conceive and in 100 women have 1 miscarriage.

Research opens hope for unlucky couples

According to the report of the research group in Nature Medicine , the culprit causing this condition is an enzyme named SGK1 in the lining of the uterus. If the level of SKG1 is too low, it will lead to miscarriage while too high SKG1 will lead to infertility.

After the embryo is inserted into the uterus, the lining of the uterus develops into a special structure called decidide, which allows the embryo to make the nest and placenta grow. If the uterus is less enzyme SGK1 , decidide cells are more susceptible to oxidation, enabling chemical reactions to occur in the cell and leading to miscarriage.

However, if the textbook 1 is too high, it will make conception difficult. When scientists proceeded to implant additional SGK1 into the wombs of the mother rats, these mice were then unable to conceive.

'Tests on mice show that the temporary loss of textbook 1 is necessary for the uterus to easily receive the embryo. However, if this process continues during pregnancy, there will be many problems, including bleeding, signs of miscarriage , 'said Prof. Jan Brosens, who led the study at the Institute. Imperial's Reproduction and Biological Development says.

Research results open up future infertility treatments. Infertile couples can use drugs to block SG1 before in vitro fertilization.