Raise blood vessels

Experts have come up with a more effective way to raise blood vessels in the heart and limbs, an important step in treating heart disease.

The method of Associate Professor Aaron Baker (University of Texas, USA) allows recovery of damaged blood vessels just by injecting a liquid. Once inside the body, it stimulates cell growth and promotes new vascular development from previously vascular blood vessels. This method has been successfully tested in mice and the results of the study have been published in the latest issue of the Proceedings of the National Academy of Sciences .

Foot after mouse, before and after being treated with new method - (Photo: Science Daily)

The ability to raise blood vessels can be very important in the treatment of chronic myocardial ischemia, which reduces blood flow to the heart, lower extremities and eventually leading to multiple organ failure and failure. The disease occurs when the coronary artery is blocked by fat accumulation, also known as fat. Such fatty areas are often the result of an unhealthy diet or prolonged smoking, among other factors such as age, high blood pressure and diabetes. Doctors often treat ischemia by opening a blocked artery with a stent or surgery to open a new blood circulation to less pumped tissue. However, both ways are limited in that it does not promote long-term effectiveness.

The method of Baker and colleagues is a combination of fibroblast growth factor 2 (FGF-2) - which is capable of stimulating growth, proliferation and cell division, as well as wound healing. - with 1 receptor embedded in liquid to increase activity. The growth agent was injected into the ischemic mice in the hind leg and it stimulated a complete recovery of ischemia in just 7 days."We hope the study will bring more effective treatments for ischemic disease," Baker concluded.