Australia found the key to cure HIV / AIDS

A group of Australian scientists have discovered the "key" in treating HIV / AIDS "century disease" as well as other immune-related diseases, which is to enhance the system's ability to respond. Immune on human body.

The group of scientists led by Professor Marc Pellegrini, currently in charge of the Infection and Immunization Center of Melbourne's Walter & Eliza Hall Research Institute, has succeeded in treating an HIV-like infection syndrome. on mice with enhanced function of living cells and immune system.

HIV virus

Professor Pellegrini said, the results of the study will provide a better solution based on the long-term ability of the immune system to respond. He pointed to viruses such as HIV and hepatitis B and C that overwhelmed the immune system, leading to the formation of chronic and incurable chronic infections.

Although there have been many attempts at treatment, the virus is still not much affected by the long-term ability of the immune system to be damaged by the virus and the immune system in general, and T cells in particular have not. The ability to " fight " against the virus. Some people have come up with the term " immune fatigue " to explain this phenomenon.

The study found the mechanism of " immune fatigue" and allowed the control of the original genes to determine whether the immune system's ability to respond to the disease could be enhanced. .

Reportedly, the team focused on Interleukin-7 (IL-7), a natural hormone for the immune system. Professor Pellegrini said: "We found that IL-7 enhances the immune system's ability to respond perfectly. The infected animal can destroy the virus itself without too much damage. tissue. "

Subsequent investigations showed that at the molecular level, IL-7 "switched off" a gene called SOCS-3 and with the disabling of SOCS-3, the mouse could maintain stimulating feedback. translate to fight the virus.

The team member, Dr. Simon Preston, said the key to success was to determine that the SOCS-3 gene could only be "switched off" when it was inside the T cell. It allowed reactions. Immunity increases the number of antiviral and immune-stimulating T cells just enough to kill the virus without activating an immense immune system.

The study by Australian scientists promises to find an effective treatment for chronic infectious diseases such as hepatitis B, C, tuberculosis and especially " disease of the century" HIV / AIDS.