Detection of genes against bacteria from mammals in Australia

The molecules present in the body of Wallaby (kangaroos) and young platypus are considered highly effective in destroying a range of multi-drug resistant bacteria.

Researchers working at the University of Sydney, Australia have discovered genes against the threat of multidrug-resistant bacteria in animals called: Wallaby (kangaroos) , which are used to only about 30 species of mammals have pockets, smaller in size than a kangaroo or wallaroo and platypus (Platypus) are small-sized, dark brown, hairy mammals with feet membrane and duck-like mines. The results of this study were published in PlosOne Magazine .

This is the result of collaboration in scientific research with the Victorian Base of Industry, and the University of Melbourne, Australia. Scientists discovered multidrug-resistant bacteria that are present inside Wallaby's body (kangaroos) and young platypus, which are highly effective in destroying a wide range of multidrug-resistant bacteria or viruses (viruses) spread.

"These molecules could be a precursor to the development of new drugs to fight multidrug-resistant bacteria , " said Emily Wong, a Ph.D. and researcher from the Department of Veterinary Veterinary Sciences. Sydney, Australia said.

The phenomenon of antibiotic resistance is a major threat to human health. Common antibiotics are currently in danger of losing their therapeutic effect against the emergence of multidrug-resistant bacteria.

Mammal mammals in Australia, currently owning a potential genetic resource, help produce new antibiotics. We have identified 14 antibacterial genes from the small kangaroo named Tammar Wallaby and 8 antibacterial genes from platypus, Dr. Wong said.

"The immature young animals of these mammals have inherently inadequate immune systems to counteract multidrug-resistant bacteria, and to survive in the environment with many of these bacteria, Young animals must rely on antibiotic sources in their breast milk, as well as their own production, " explained Dr. Wong.

This study tested 19 antibiotic-resistant bacteria, which are resistant to at least three antibiotics.

"A Wallaby species (KaKlebsiella pneumoniaenguru) has a very strong antibacterial ability, especially against multi-drug resistant bacteria, including: Bacteria Pseudomonas aeruginosa (also called green pus bacillus); Drug resistance and bacteria Acinetobacter baumannii is resistant to many different antibiotics that cause dangerous and even life-threatening conditions of patients with immune system damage , " said Associate Professor Kathy. Belov, the leading author of the study.

Mammal mammals in Australia, now a valuable untapped source of medicinal herbs. Research mechanisms to protect immature young animals of these mammals, to be applied to protect the human body from the spread of multidrug-resistant bacteria and new viruses appeared, according to Dr. Belov.

In the future, Professor Ben Cocks, working at the Victoria Industrial Facility, will focus on studying the ability to use synthetic computers and techniques to detect new antibacterial chains including Antimicrobial ability of ancient marsupials.