Extremely dangerous combinations of medicines!

Use the medication as directed by the doctor - this is well known. However, in our country, many people often guess their own diseases, buy their own medicines without knowing that there are drugs used together at the same time will cause extremely dangerous reactions to the body.

According to an incomplete statistic, nearly a quarter of people aged 30-65 may have to use multiple drugs at the same time to treat illness. The use of many drugs at the same time is necessary when patients have many diseases, but the wrong combination of these drugs can have serious consequences.

Cholesterol-lowering drugs + vitamin B3 or antifungal drugs

Vitamin B3 or vitamin PP, active ingredient is nicotinic acid (niacin) or nicotinamide (the amide form of nicotinic acid). Vitamin B3 helps reduce cholesterol, helps with blood circulation and nervous system formation. It also interferes with the synthesis of sex hormones. By stimulating the synthesis of keratin, vitamin B3 participates in improving skin beauty and hair. However, this tonic can be harmful to muscles if you take it in combination with a statin group of drugs also has a cholesterol-lowering effect. Both vitamin B3 and statins weaken muscle weakness to the extent that patients are more likely to experience cramps or aches. Combining these two drugs will cause reactions such as rash, dyspepsia, and an increased risk of rhabdomyolysis.

Fluconazole is a popular antifungal medicine, prescribed by many doctors and people can buy it for themselves. It will be normal if the patient is not in the process of taking statin drugs to lower cholesterol. Statin is one of the most prescribed drugs in the world. The combination of statin and fluconazole duo has the potential to cause muscle weakness or kidney damage.

When having to use a variety of medicines, users need to be aware of drug interactions.(Illustration).

Decongestants and antihypertensive drugs

Decongestants, especially those containing pseudoephedrine, constrict vasoconstriction, help reduce swelling and reduce nasal discharge. However, this drug can constrict the blood vessels in the body, which increases the risk of hypertension, against blood pressure medications and is dangerous for people with high blood pressure. Therefore, if the patient is taking blood pressure medication, decongestants should not be used at the same time. Currently, in some cold medicines also contain decongestants, so blood pressure patients should carefully review the ingredients before use.

Omega-3 and anticoagulant

Omega-3 supplementation is essential, beneficial to the heart, but this type of fatty acid also acts as a blood vessel. Therefore, if the patient is taking an anticoagulant such as warfarin or aspirin, it may increase the risk of bleeding if taken together with omega-3.

Analgesics + antidepressants

Some special antidepressants, such as selective serotonin-SSRI reuptake drugs (fluoxetine, fluoxamin, sertraline, paroxetine, citalopram, etc.), work to increase the amount of serotonin in the synaptic thereby improving the effectiveness. results of depression state. Some pain relievers containing tramadol hydrochloride may also have the same effect. When using SSRI with tramadol, they will work in the same way to increase excessive serotonin levels causing serotonin syndrome. If used in high doses, these two drugs can cause irritation, high body temperature, faster heartbeat and rapid breathing.

Use two types of cleaning solutions at the same time

A Chinese woman uses toilet bowl cleaner with poison solution. Then she fainted, died due to not being treated promptly.

The doctor explained that the mixture of toilet and detergent solution reacts with each other to produce chlorine gas. This gas enters the human body through the respiratory tract, causing the respiratory tract mucosa to become inflamed, making it difficult to breathe. Serious cases can be fatal.

Use sunscreen + Cephalosporins

Take anti-sunscreen medicine and use two more Cephalosporins antibiotics, a 60-year-old patient in Ningbo (China) who must go to emergency in a red face, lowering blood pressure.

Antidepressants combined with Cephalosporins antibiotics cause liver damage.

Explaining the above case, doctors said that anti-sunscreen drugs contain alcohol, which will produce ethanol. Meanwhile, Cephalosporins antibiotics inhibit Ethanol. Together, these two drugs cause the body to accumulate ethanol, thereby causing liver damage, apnea, and even death.

Take antihypertensive drugs + eat grapefruit

To lower blood pressure, a Hubei man drank two antihypertensive pills and ate half a small grapefruit. Half an hour later, he felt an intense headache, heart palpitations had to be hospitalized.

In grapefruit, especially grapefruit, there are active ingredients that make the drug quickly absorbed into the blood just like when increasing the dose. If you eat grapefruit and take antihypertensive drugs at the same time, the effect of the drug will increase from several times to several dozen times, causing nausea headache very dangerous. Ideally, pomelos should be avoided 72 hours before and 6 hours after taking antihypertensive drugs.

Mosquito repellent + apply sunscreen

The main ingredient in mosquito sprays is Diethyltoluamide and alcohol, while sunscreen contains Benzophenone. A mixture of Diethyltoluamide, alcohol and Benzophenone with high temperature on the skin will increase the absorption rate, making sensitive individuals more likely to develop allergies like a Taiwanese woman. She had a rash all over her arms and legs and fainted due to applying sunscreen right after spraying mosquitoes.

Also, note the following cases

Flu medicines such as Paracetamol, Paracetamol and Amantadine Hydrochloride compounds all contain Acetaminophen, and when meeting honey, complex substances can be used to reduce fever-reducing effects. Drugs containing honey such as cough syrups, high tea paints are not suitable for use with top cold medicines.

Do not combine Vitamin C with Sulfonamide because of the risk of precipitation causing urinary tract stones.

Iodine in alcohol Iodine will react with mercury in Merbromin to produce a reaction, producing Iodine mercury that accumulates in the skin, causing harm to the body.

Advice of physicians

Each drug has its own effect, with different properties and reactions, which have different effects on the parts of the human body and work in time.When having to use a variety of medicines, users need to be aware of drug interactions . Even the most common and common medicines can still react to other drugs when taken together. Therefore, at the same time taking many drugs will affect the absorption, distribution, exchange and excretion as well as the interaction between drugs.

To be safe when using medicines to treat diseases, patients need to strictly adhere to the doctor's orders. Do not arbitrarily use drugs, do not use overdose. Be sure to tell your doctor what medications are being used. When using many drugs, consult a physician about the time of medication administration. Each person should create a habit of carefully reading the instructions before using the drug to know the necessary information when using the drug and adverse drug interactions, avoiding the unfortunate reactions that may occur.