Observe visceral cells through laser microscopes

Professor Nan Masato and colleagues from the Mie University School of Medicine, Japan, have successfully studied the system of observing the internal cells in living mice through laser microscopes.

It is known that this system can clearly observe the status and process of the drug when the cancer cells in living organisms move. This new finding has important implications for preparing new drugs.

Illustration.

Normally, laser microscopy can only observe cell activity in living organisms at a depth of about 1 ml. However, because the heart of a live animal that continuously vibrates the arteries in the blood vessels, in addition to respiratory factors, the laser microscope cannot observe the internal state of windpipe of living things.

This newly studied observation system will make the mouse stay in a fixed state, then take advantage of the fallout of the '2 photon laser optical microscope' to observe the state inside the mouse internal organs. .

The images obtained from the camera's "anti-vibration device" show that when making the microscope and mouse fixation device have the same vibration frequency, and between the mouse and microscope create resonance, then the mouse will remain static compared to the microscope.

Therefore, scientists have clearly observed the activity of the inner organs of mice such as liver cells and colon cells.

Through the 'anti-vibration device' scientists have successfully recorded the process of transferring the pancreatic cancer cell to metastatic liver cells of mice.

This system can observe the reaction after giving cancer-treated mice a drug, thereby applying it to areas of new drug preparation.