Stem cells can treat neurological disorders

Based on scientists' reports, human stem cells are taken from pregnancy as well as from the fetus; Both can delay the neuropathy in rats, stimulating these cells to travel throughout the brain to take on the work of damaged neurons.

This study was published in the Journal of Natural Medicine ; shows that this is the first time that embryonic stem cells from young humans have successfully treated a serious disease in animals.

Professor, Dr. Evan Snyder of the Burnham Institute for Medical Research in La Jolla, California; The lead researcher said his team hopes to test their method soon on children suffering from a disease called Sandhoff; is a brain disease - very dangerous .

In the Journal of Natural Medicine, the researchers also say that their method opens up new ways to treat serious cerebral palsy such as Parkinson's disease, Alzheimer's disease and hardening and muscular atrophy; Also known as ALS or Lou Gehrig's disease.

Snyder and his colleagues used mice with the same Sandhoff disease to use for their research purposes.

Researchers, including research groups from universities like Oxford in the United Kingdom, Yonsei University in Seoul, South Korea and other Universities, wrote in their report: 'Children The disease is in a state of mental retardation, acting in a very unusual and often premature manner.

(Photo: Dost-Dongnai)

Encephalitis is clearly the cause of brain cell death.

Synder's team used both embryonic stem cells taken from large human fetuses at maternity and human fetal cells.

They transplanted these stem cells into the brains of mice and noted that no problems had occurred. No tumors were present, mice did not " curse " strange cells that were randomly inserted into their bodies, and as a result - treatment seemed to reduce inflammation.

'They seem to have no objection,' Snyder said.

Success

70% of treated mice outlive the untreated mice. After all, the disease has returned to them, but Mr. Snyder believes that they can prevent the disease from developing by increasing the dose of stem cells to take on the functions of mutated natural brain cells. .

Stem cells are very valuable because they can produce a variety of different tissues and cell groups. But Mr. Snyder said scientists began to realize that they were even more capable of doing so.

'This proves that cell bodies are a topic worth mentioning in press conferences,' he said in a telephone interview.

'They collaborate . to try to restore the balance of a living body. They produce healthy factors. They try to restore the body of other cells and detoxify the body. '

Transplanted human cells have replaced damaged neurons and transmitted neurons. They also increase the supply of enzymes for the brain; is the substance that the body lacks when it comes to Sandoff disease.

The cause of Sandoff's disease is the mutation of the enzyme because of the enzyme, also known as Hexoza or hex deficiency; which brain cells need, to remove excess fat - also called lipids. When lipids increase, brain cells die. It is similar to Tay-Sachs disease, and Tay-Sachs or Sandoff disease has no cure.

The use of human stem cell embryos is a problem that can cause controversy, because some people believe it is wrong to destroy human fetuses for use in tests.

Snyder said his team used stem cells samples approved by the US government to fund funds. He said when his research team asked for permission from the US Food and Drug Administration for experimental treatment on children, they might not initially seek to use stem cells to do experiments. , but only fetal stem cells (from embryos removed), only.

Danh Phuong