Successful restoration of vision in mice by gene therapy

Future hopes can cure increased vision loss in humans after a group of successful scientists restored the eyesight of mice, using new improved gene therapy techniques .

A group of American scientists from the National Institutes of Health used gene therapy to reprogram invisible retinal cells, and then used them to replace vulnerable light-sensitive cells. .

Picture 1 of Successful restoration of vision in mice by gene therapy
New gene injection helps restore vision in mice.

This is the first time that successful researchers have replaced damaged retinal cells, leading to the hope that someday in the near future, the same process could be applied to humans.

Research has demonstrated that it is possible to restore lost light-sensitive cells in the eye, by placing a gene into retinal cells and using it to reorient them. This method allows the mouse to regain sight after about six weeks.

However, in the study, only rod cells were recovered, providing visibility in low light mode.

But the researchers hope that preserving rod cells will also protect cone cells, another form of retinal cells needed for vision.

Dr. Bo Chen, one of the researchers, said: 'This is a very powerful cell recovery mechanism. The main strength of the study is that it can be applied to a wider spectrum of retinal degeneration. If this method works, it can change the way we treat patients with retinopathy and can learn how to treat other types of eye diseases like cataracts. '

Picture 2 of Successful restoration of vision in mice by gene therapy
If this method works, it can change the way we treat patients with retinopathy.

Dr. Chen added that the human eye has the same basic structure, although this process is not yet possible in humans. He explains: 'The basic structure is still there. But for some reason, it's banned. '

Scientists have studied zebrafish as part of the investigation, which has the ability to transform retinal nerve cells into important rod cells.

Helen Lee, from the Royal National Blind Institute, welcomes this news: 'It's clear that this research is still in its early stages. But at some point in the future, stem cell therapies will probably become one of the treatments for vision-threatening eye diseases.

If this process can be carried out on humans, with newly created rod cells, it can give vision to many people who are born blind or restore vision to others.