Anti-itching solution when mosquito bite is very simple

Unless you have a great tolerance, the urge to scratch the mosquito's bites, the easiest and most effective way to fight itching is to use antihistamine anti-allergy medicine or a cold stone.

When a female mosquito burns you (they use human blood to raise eggs, the male mosquito has no reason to burn people), it injects saliva below your skin. This saliva contains anticoagulants to make mosquitoes easier to absorb your blood.

When a female mosquito burns you, it injects saliva beneath your skin.

A 2012 study published in PLOS ONE has revealed what happens when a mosquito bites an anesthesia mouse under a microscope. You can see the mosquito's brown hose detecting the pink blood vessels, penetrating it and starting to smoke. Blood vessels shrink when the insect starts drinking the victim's blood:

According to the American Institute of Allergy, Asthma and Immunology, mosquito saliva activates your immune system to release histamine to the mosquito bite, leading to an inflammatory reaction that causes the area to become red and swollen. At this point, your natural reaction may be to scratch the uncontrolled itch. However, that action can scratch the skin, allowing bacteria to enter the inside causing infection.

The US Food and Drug Administration (FDA) recommends that before an itch becomes too much, apply to a mosquito bite on an antihistamine allergic cream or gel or take an antihistamine pill.

Look for medications that have "Diphenhydramine" in their ingredients list. Both creams, gels, and pills are widely sold in pharmacies at relatively cheap prices.

A cold stone rubbing on the mosquito bite can work to soothe the itch.

Studies have also shown that cold can reduce the sensation of pruritus arising from histamine substances. Therefore, a cold stone rubbing on the mosquito bite may work to soothe the itch in case you do not have antihistamine available.

For all diseases you are at risk of getting from mosquitoes, including Zika virus and dengue fever, the most ideal option is to avoid mosquito bites first.