Be careful when taking aspirin

Aspirin has many therapeutic effects such as prevention of platelet aggregation, prevention and treatment of thrombosis in blood vessels (such as thrombophlebitis) and prevention of myocardial infarction, limiting the risk of rectal cancer, actually However . the opposite side of aspirin is also abundant, it should be avoided in some cases.

Should take aspirin at full to avoid unfortunate accidents (Photo: greatbigstuff) The name 'aspirin' was officially born in 1899. Initially it was made in powder form, and one year later it was sold in tablet form. Nowadays aspirin is quite popular with many brands (trade names) and in many forms: tablets, capsules, powder pills, effervescent tablets, aspirin pH8 tablets .

Aspirin and Reye's syndrome (HCR)

Children and teens who take aspirin in certain circumstances may be at risk, which is Reye's syndrome (HCR). HCR named after Australian pathologist Douglas Reye - first described the disease in 1963 in a hospital in Sydney. HCR consists of two symptom groups: acute brain syndrome and fatty degeneration in viscera (brain, kidney, heart, especially liver), very severe disease with a high mortality rate.

According to statistics, for every 2 patients who can only save 1, the surviving child is also seriously injured in the brain. Most children have a fever caused by flu, or chickenpox, and are given aspirin, then vomiting, unconscious, sometimes having seizures, leading to rapid death. From the mid-80s of the twentieth century, the UK Pharmaceutical Safety Commission announced a recommendation: 'Do not administer aspirin to children under 12, except for rheumatism'.

In the Federal Republic of Germany, the Ministry of Health has decided to add in the application to guide the effects besides the effects of aspirin. In the state of Michigan (USA) from the 80s of the 20th century onwards, thanks to widespread information about the risk of HCR arising from children taking aspirin every time they get chickenpox, HCR has decreased markedly despite the disease. Chickenpox still exists every year.

Aspirin with asthma patients

Asthma patients should not take aspirin, because it makes asthma worse, even life-threatening. Aspirin can cause a reaction to an asthma attack that is not immune, so it is also called a dummy allergy, or a specific reaction. The mechanism of causing asthma . of aspirin has not been thoroughly understood, only it is related to many factors, especially the imbalance of arachidonic acid metabolism, increasing the release of intermediates from the cells ( mastocyte) bronchial, proinflammatory intermediates, prostaglandins and leucotriene .

Asthma caused by aspirin usually occurs in people with a history of allergies (allergic rhinitis, those who have had stable asthma attacks .), an acute episode of aspirin, millions of The disease usually occurs 2-3 hours after taking the drug, with severe, prolonged symptoms, even death.

Some other cases to note

Aspirin chemical model (Photo: bris.ac.uk)

- Because antiplatelet properties increase bleeding, no bleeding, menstrual women should not take aspirin, especially those who are suffering from menorrhagia, haemorrhage not taking aspirin to reduce fever, relieve pain . People with bleeding or bleeding are also not allowed.

- Pregnant women in the last 3 months should not take aspirin because it can prolong pregnancy, and drugs can be toxic to the fetus, causing bleeding in newborns, women who are prone to hemorrhage during delivery. Nursing mothers also do not take aspirin, because the drug is absorbed through breast milk, potentially poisoning the child.

- People with peptic ulcer disease - duodenal administration should not take aspirin, because aspirin facilitates gastric acid and pepsin enzyme to cause damage to the stomach lining after the protective barrier is weakened. It increases the ulcers that are inherent in the stomach, can even bleed, or worse, puncture the stomach.

- Those who have liver, kidney failure, and anemia (because aspirin reduces the red blood cell life) are not allowed to take aspirin. People who are taking anticoagulants, methotrexate absolutely do not take aspirin.

- Do not drink alcohol when taking aspirin, because alcohol increases the irritation of the stomach lining of aspirin. Aspirin itself is acidic, which can make the digestive system uncomfortable, so take it at full time.

- In addition, although aspirin is less toxic, easy to drink, but if used long-term, it can cause nausea, vomiting, tinnitus, deafness, confusion . When there is a need to reduce fever, relieve pain . all people should not arbitrarily take aspirin, but need to go through medical staff to guide the use of medication.