Blood type change after blood donation

Researchers at the University of British Columbia have found a way to change donated blood types.

Try to change the blood type after donating blood type for O blood type

Researchers at the University of British Columbia have found a way to change donated blood types. By using enzymes to cut off antigenic components in the bloodstream, they can convert all blood groups to O - blood types. A great study, which saved the lives of countless patients without the blood shortage.

Perhaps we should donate blood several times in life because this is a very human and meaningful action. But if you have blood type O you will be advised to donate more often because this is the most useful blood group but quite rare. From a biological point of view, the differences between blood types A and B are determined by a type of antigen that has an adherent component on the surface of red blood cells. Difference is simple, but just the wrong blood type can lead to death . For example, transfusions of blood A and blood O, their immune system will immediately attack the " invaders " carrying different sugar molecules.

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By using a special enzyme , researchers can remove antigens on red blood cells, and produce a neutral type of blood . This is not the first time people have made less blood in the laboratory, but this effort has produced the best results ever. The researchers used a technique called direct evolu- tion : using bacteria to form enzymes and insert specific mutants into bacterial DNA to increase the enzyme activity required. After cultivating the bacteria for five generations, the enzyme has a 170 times more potent activity than before.

And finally, enzymes will be used to cut off antigens from red blood cells. Although this enzyme is capable of removing most of the antigens, this process is not perfect. In other words, the type of blood O is formed is not perfect, which requires the addition of enzymes into the blood that has been donated. Researchers are continuing to increase the effectiveness of the enzyme and are confident that the study will soon advance to clinical trials in the near future.