Eating too much sugar causes sexual endocrine disorders

According to a new study by scientists, daily intake of too much sugar will disturb sexual hormones, thereby increasing the risk of many diseases, including cancer.

According to research by Canadian experts, published in Clinical Investigation, high levels of fructose and glucose in the blood can invalidate a gene that controls the concentration. Genital hormones in both men and women.

They are the SHBG (sex hormone binding globulin) gene, a protein that binds to the hormone hormones testosterone and estrogen produced by the body. When the concentration of SHBG in the blood decreases, the disorder of these hormones will occur.

SHBG works to regulate the levels of testosterone and estrogen circulating in the body. Therefore, reducing SHBG will make the body ' feel ' inadequate hormones, so producing more testosterone and estrogen, despite the existing levels of these two hormones in the body.

According to experts, it is recommended to replace simple sugars (such as sand sugar, glucose and fructose) with complex sugars, such as starch (Photo: ps.uci.edu). Consequently, testosterone and estrogen levels will increase. Overly high, increasing the risk of acne, infertility, walled ovarian syndrome and uterine cancer in obese women. At the same time, reduced SHBG status also affects the ratio of estrogen and testosterone, making women more at risk for heart disease.

The research team suggested that simple sugars, such as sucrose, glucose and fructose, should be replaced with complex sugars (complex carbohydrates), such as starches. Fructose sugar is abundant in sugary drinks, syrup and many other sweet products. When introduced into the body, simple sugars (glucose and fructose) enter the liver and are metabolized there; excess sugar will be stored in the form of lipids by the body.

By examining cultured cells of mice and humans, experts found that excessive synthesis of fat would inhibit SHBG activity, causing the concentration of SHBG to drop sharply in the blood.

Lead researcher Dr. Geoffrey Hammond, scientific director of the Children and Family Research Institute in Vancouver, Canada, said: 'With this new knowledge, we can now use SHBG as a Only biomarkers to monitor liver function better before symptoms arise. We can also use it to determine the effectiveness of dietary changes and drug use to improve liver metabolism '.

Previously, scientists believed that high levels of insulin reduced SHBG, because obese people and those with diabetes tend to have high insulin levels and low levels of SHBG in the blood.

Quang Thinh