H1N1 virus becomes 'killer' if there is 1 more protein
According to a recent study, one thing is that the A / H1N1 flu virus only lacks one thing to be turned into a "killer killer," which is a protein found in Spanish flu, the type of molecule that causes a great year. 1918 claimed the lives of tens of millions of people.
Spanish flu virus has claimed the lives of tens of millions of people.(Source: Internet)
Scientists studied the 1918 Spanish flu virus to find out which factors caused mass deaths in the early 20th century. This terrible virus has killed tens of millions of people, one in the worst disasters in human history.
Scientist Peter Palese of the Sinai Mount School of Medicine in New York found that the Spanish flu virus has a 'killer' structure on its surface that consists of three proteins, neuraminidase (referred to as N in H1N1). ) and hemagglutinin (letter H in H1N1) and another protein called PB1-F2.
The structure of the three proteins makes a 'killer weapon' a million times more toxic than the regular seasonal flu virus.
According to Palese, while two surface proteins are important factors, PB1-F2 is actually a "big leap" of Spanish flu in terms of murder.
Currently, Palese and his colleagues have discovered that the PB1-F2 protein plays a role in preventing the body from making an important antiviral compound, interferon. Without interferon to help inhibit, the flu virus can proliferate and overwhelm the immune system just three days after infection.
Viruses that cause other pandemics, such as 1957 and 1968, also have the PB1-F2 protein. However, the 2009 H1N1 swine flu virus lacks this deadly protein. "The swine flu virus is not as dangerous as other pandemic flu viruses in history," Palese said.
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