Hope to cure cancer from the 2018 Nobel Prize in Medicine

By stimulating the immune system, research by James P.Allison (USA) and Tasuku Honjo (Japan) gives hope to completely reverse cancer.

On October 1, the 2018 Nobel Prize in Medicine was awarded to scientists James P.Allison (USA) and Tasuku Honjo (Japan) for finding a treatment for cancer by inhibiting the harmonic mechanism. Antibody properties, also known as checkpoint immune system therapy. This is the first study of cancer treatment that won the Nobel Prize.

At the announcement ceremony, Klas Kärre, a Nobel committee member, said both Professor Allison and Professor Honjo found that immune cells could act as a brake set to attack cancer cells.

In 1990, Professor Allison found a type of protein that acts as a brake, or checkpoint, in the immune system. He demonstrated that brake release frees cancer-fighting immune cells, thereby providing positive results in cancer treatment in mice.

In 1992, Professor Tasuku Honjo found a second test score. His discovery-based therapy also proved effective in repelling cancer.

In fact, the idea of ​​mobilizing cancer-fighting immune systems was first introduced more than a decade ago. However, by the time Professor Allison and Professor Honjo, the idea became clinical treatment.

Simulate the braking system of the immune system.(Photo: Twitter).

Mr. Kärre identified Professor Allison's work and Professor Honjo as a major turning point, while changing the outlook on cancer treatment. Instead of focusing on tumors, therapies created by the two scientists are directed towards the immune system, thus suitable for many different types of cancer.

Drugs from Allison's work and Professor Honjo, called test point inhibitors, show clear results in patients with lung cancer, kidney cancer, melanoma and lymphoma. lymph. They cause side effects but are not serious and can be reversed.

"Thanks to this therapy, we can cure cancer , " Kärre said.

According to The Guardian, after learning of his Nobel Prize, Professor Alisson is in a "state of shock" for achieving "every scientist's dream". In Japan, Professor Honjo celebrated with colleagues at Kyoto University. Both will split the prize worth nine million kronor (about $ 1.1 million).

Professor Allison was born in 1948, currently working at the University of Texas Anderson Cancer Center. He had many years of research on the mechanism of T-cell receptor activation and activation and was also the first scientist to find a way to isolate complex protein sequences of T-cell receptor antigens.

Professor Allison lost her mother at age 10 because of lymphoma. Growing up, witnessing the pain of chemotherapy, radiation therapy urged him to find a way to treat cancer. Although he claims to be just a simple scientist who wants to understand T cell activity, Professor Allison acknowledges what happened "always in my head".

Professor Allison (white shirt) celebrates with family and friends.(Photo: Twitter).

Professor Honjo was born in 1942. He began to study cancer after a classmate died of stomach cancer. Professor Honjo is known for his work on protein PD-1 and discovered an AID enzyme that is essential in the process of recombinant antibody and super-mutant genes. Since 1984, Professor Honjo has worked at Kyoto University.

Professor Honjo (blue shirt, blue vest) celebrates with his colleagues.(Photo: Twitter).

Although they are all over the age of 70, both Professor Allison and Professor Honjo affirmed that they will continue to work to bring hope to cancer patients."I want people with cancer outside to know that we are still working , " Professor Allison said.

Professor Honjo said: "A golf player came to thank me that thanks to my work, he had cured lung cancer. Such words are more valuable than any award. I will not stop let immune system therapy save many patients ".