How does cold plasma support healing open wounds?
Cold plasma can directly affect open wounds that change the environment to help wounds heal faster.
Dr. Do Hoang Tung, Vietnam Academy of Science and Technology, author of cold plasma beam projector explains this mechanism. He said that for cold plasma to help commercial injuries can be divided into 3 main effects.
First , plasma destroys microorganisms that interfere with healing processes such as bacteria, viruses and fungi. In contact with plasma microorganisms can break down their cell membranes by bombardment of ions and electrons as well as corrosion of free radicals, active substances. Free radicals and ultraviolet rays can also penetrate the cell membrane of microorganisms to lose the activity of proteins that make microorganisms unable to function.
Cell membranes of E. coli are destroyed when exposed to plasma.
Not only does it kill single bacteria, plasma also destroys biofilms produced by bacteria. The formation of biofilms helps the bacteria to better withstand adverse conditions, making the wound unable to heal.
Not only does it kill normal bacteria, plasma also kills antibiotic-resistant bacteria. Because plasma is a physical agent, and multi-agent, bacteria cannot be modified to form plasma resistance. For plasma, common bacteria or antibiotic resistant bacteria are destroyed.
The impact of plasma in the healing process.
Secondly , plasma can polymerize body fluids in the wound to form a membrane of proteins to protect the wound floor, to re-invade bacteria.
Third , plasma helps the body release the wound-healing growth elements so that the wound is faster. The support effects can be listed as: increased blood circulation, increased vascularity, kill endotoxins, reduce inflammation, reduce pain, increase cell proliferation, increase collagen, stimulate epidermal regeneration.
The process of wound healing usually goes through three main phases: inflammation phase, proliferation phase and regeneration phase.
In this process, the plasma supports very well for the first two phases, the inflammation phase and the proliferation phase make these phases faster so that the wound is also faster and more normal, indirectly helping the regeneration phase. advantageous, reduce formation of contraction causing bad scars.
Plasma is an ionizing state so the composition of the plasma always contains electrically charged particles of ions and free electrons, making the plasma very conductive. Besides charged particles, it is a high-energy plasma state that still glows, containing free radicals and active ingredients. These components, when exposed to environmental changes, create many applications of plasma.
Cold plasma is plasma at room temperature, so it can directly affect open wounds that change the wound environment to help open wounds faster.
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