International publication of the Vietnamese genome sequence

The study shows that genetic independence reflects the very high resistance of Vietnamese people and is far from the Han Chinese genome.

The Vietnamese genome research project was carried out by scientists from Vinmec Research Institute of Stem Cell Technology and Genetics recently published in the international genetic journal Human mutation . Genetic analyzes of the research group show that Kinh and other ethnic groups in Southeast Asia share ancestors.

Researchers found 25 million variants after solving gene sequences in Kinh people.(Photo: DNAtix).

Results from different genetic analyzes are consistent and reinforce the hypothesis that people migrate from Africa to Asia according to the route from the South to the North instead of from the North to the South. The data also show that Kinh and Thai have similar genetic structure and close evolutionary relationships.

The team took blood samples and sequenced the entire genome and genome of 305 Kinh people, combined with the genetic data of 101 previously announced people, found 25 million mutations, of which more than 99% variation with repeating frequency of more than 1%. The study also revealed a large number of mutations called pathological mutations and showed that genetic independence reflects the very high resistance of Vietnamese people, far from the Han Chinese genome. This has important implications, is the reference basis for many medical studies - The next birth on Vietnamese health is related to the genome.

According to the research team, structural variations in the Kinh population though play an important role in genome research but have not been done in this topic. Researchers are exploring other methods such as micro-comparative genetic hybridization to build a structural variation database for Kinh and Southeast Asian populations.