Molecules inhibit arteriosclerosis?
German scientists have discovered that a form of molecule can inhibit the formation of arteriosclerosis plaque.
Scientists say their next goal is to study the corresponding drugs on the basis of the results, and hopefully for years to come on the market.
Arteriosclerosis mostly occurs because blood accumulates inside a broken blood vessel wall, leading to a blockage of blood vessels.
Eating lots of vegetables can prevent the development of atherosclerosis.Illustration. (Source: Internet)
If this blockage goes straight to the heart or to the brain's aorta, it can cause diseases such as heart attack or stroke.
CD40 and its ligands like CD40L are a pair of molecules involved in the body's immune response. Previously scientists have discovered, this molecular team has played a key role in the process of forming plaque.
If it is possible to inhibit this molecule, it can inhibit the formation and breakdown of plaque.
Scientists from the Aachen Industrial University in Germany said they have solved the conflict, the key point of this solution is a special conjugate protein TRAF6.
When experimenting on genetically modified mice, the scientists found that when controlling TRAF6 will simultaneously inhibit CD40 and CD40L, thereby inhibiting the formation of plaque, and thereby help protect the immune system in the body.
The results of this study were published in the latest issue of the American Journal of Experimental Medicine.
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