Create artificial molecules against drug-resistant bacteria

Scientists have just taken another step in the fight against drug-resistant bacteria by making artificial molecules.

The research team at the University of Melbourne and the Southwestern Australian Medical Center have developed a mixture of artificial molecules that can withstand and overcome stubborn drug-resistant bacteria, providing better treatment opportunities. and create a better immune system for patients.

Picture 1 of Create artificial molecules against drug-resistant bacteria
Two new inventions from Australian scientists can eliminate stubborn resistant bacteria with artificial molecules.

Scientists at the University of Melbourne use star-shaped peptide polymers or short protein sequences, to directly kill bacteria through bacterial cell wall tearing. This method is not only effective, but also very safe. When tested on red blood cells, the results show that safety is 100 times higher than chemical methods.

At the Southwest Medical Center, researchers used molecules from the PPMO compound (morpholino oligomer peptide phosphorodiamidate) to prevent the movement of bacteria that could resist the drug. They rely on the activity of RNA or DNA, linking artificial genetic sequences to bacteria, preventing protein synthesis. The method of using PPMO is not a way to kill, but it makes resistant bacteria become weaker and do not function with its proper function.

Both methods are feasible and have been tested in practice. However, its widespread application is still delayed because it depends on each person's physical condition. When necessary, doctors can use both methods to achieve the best result of eliminating completely resistant bacteria.