New algorithms predict molecular behavior and tooth decay drugs without filling

An international team of researchers has developed a machine learning algorithm that can learn and model complex molecular behaviors. Research to lay the foundation for the development of new pharmaceuticals, improve the efficiency of batteries, solar batteries .

Simplify the complexity

Although there are many warnings about the dangers of artificial intelligence, it is undeniable that technology has changed our daily lives. Image recognition, text analysis and language translation tools allow us to see the world in completely new ways. Moreover, mobile devices can now predict many behaviors based on human past actions.

A group of researchers used machine learning to predict molecular behavior. This 'foresee' is much more complicated than predicting the user's next actions on a smartphone. The prediction machine that the manufacturing team is really a feat is because it requires complex quantum calculations. The study was published in Nature Communications.

The researchers 'trained' the algorithm using a simple molecule called malonaldehyde. They then adapted to predict the complex behavior of the molecule and proceed to compare the machine's predictions with the current chemical knowledge they knew about malonaldehyde. The team found that the machine could learn molecular behavior using limited data during the time it was trained.

Speaking to the press, researcher Mark Tuckerman of New York University said: "By defining patterns in molecular behavior, the algorithm provides fundamental principles of atomic interaction in one. We can then extract information to predict new phenomena. "

This is another example of the impact of artificial intelligence on the industry, from medical research to psychology and behavioral science. Research shows that machine learning methods can be used to perform difficult tasks in everything - as long as the system is provided with sufficient data.

Use AI to predict molecular behavior.(Photo: Internet).

The ability to predict this molecular behavior greatly contributes to the development of pharmaceuticals, as well as to improve the performance of batteries, solar cells and digital displays. Basically, any work involving complex quantum mechanical calculations, to simulate atomic or molecular interactions benefits from this study.

According to Müller, the machine can create behavioral patterns but does not need to use complex calculations, this is the outstanding advantage of new research. Müller added: "Now we not only use artificial intelligence to learn data, but also to better understand our science and to have new insights."

Goodbye to filling

While developing drugs for Alzheimer's patients, scientists accidentally discovered that the drug could be used to treat tooth decay.Tideglusib stimulates stem cells in the pulp to create new enamel and repair natural teeth naturally.

New discoveries about Tideglusib may lead to 'extinct' fillings . Its advantages are the creation of a new mechanism for self-replicating teeth without medical intervention.

Normally, teeth can regrow themselves without external support, but only in certain cases. Only when the pulp is affected by tooth decay or trauma will they produce tooth enamel. But at that time, the teeth could only be recreated with a very thin layer - not enough to "cope" with tooth decay.

Tideglusib can change this because they neutralize GSK-3 enzymes , preventing natural enamel from forming. There is a small, decomposing sponge made from collagen. When inserted into the cavity, the sponge stimulates the growth of enamel within 6 weeks and filling deep holes. At that time, the collagen structure will dissolve, and the teeth will be completely renewed.

So far, the method has only been used in rat teeth. However, according to Paul Sharpe, Professor of Dentistry at King University, London and the lead author of the study, 'Tideglusib has been clinically tested for Alzheimer's disease and provides an opportunity for this treatment to be fast. quickly applied in the clinic '.

"The ideal product due to its simplicity, furthermore, is a dental product that uses a completely natural method to protect the pulp and restore tooth enamel," he added.

New research is the perfect replacement for cementing - which makes teeth worse and worse and needs regular filling. Through scientific advances like this, people are looking for ways to enhance the body's natural defense mechanisms - the best way to combat injury and disease. If the new method is applied, you will probably be the last one to have a filling by the doctor's hand!