New discovery in the treatment of nervous system diseases
A British study published in the journal Nature on May 6 found that through experiments on mice, researchers at the University of Leicester found a way to prevent brain cell death in systemic diseases. Neurological diseases such as Alzheimer's disease, Parkinson's disease and prolonged life for patients.
They conducted relevant experiments, which used mice with nervous system diseases caused by protein accumulation caused by errors.
In humans, diseases such as Alzheimer's disease, Parkinson's disease are also caused by the above cause, so these lab rats are a good model for studying similar diseases in humans.
In the brain cells of these mice exist many shapes of faulty proteins. They constantly accumulate and cause the body's defense response, leading to a stagnant cell production capacity. Normally, if the faulty protein is destroyed, this transition will re-open itself.
However, in these mice, because the faulty protein constantly accumulates, it continues to be locked. New protein-free cells, including some proteins that play an important role in physiological activity, eventually lead to brain cell death, causing Alzheimer's disease for these mice.
Research shows that if a special protein is implanted into the brains of the mice, the corresponding transformation can be reopened. At that time, though, in brain cells with faulty protein accumulation, their life was prolonged, not only that, but their function with other brain cells also recovered, prolonging life for those this mouse.
Lead researcher Professor Giovanna Mallucci said the results were significant because many diseases of the nervous system have similar principles.
This study could help prevent brain cell death of diseased mice, meaning it could be used to treat diseases like Alzheimer's and Parkinson's in humans.
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