New hope for patients with post-traumatic psychosis
(Scientists have found nerve cells to prevent the formation of fearful memories in the rat brain called 'Hippocampus'.
These inhibitory neurons allow the creation of a memory of the context and location that is not affected by the unpleasant event that takes place at the same time.
In a report published in the journal Science, the team said that this work helps them better understand the neurological basis of post-traumatic psychological disorders in humans.
Attila Lonsoczy, a lecturer at the University of Colombia, New York, and colleagues focused on studying how Hipocampus stores specific contexts as well as separating them from fearful events.
When looking at individual neurons in the rat's brain, it is found that neural suppressor cells called 'Interneuron' play an important role in forming memories of fear before they travel. move to other areas in the brain.
In response to the BBC Science Channel, Dr. Lonsoczy said: ' Interneuron cells are triggered by fearful events, which act as filters to prevent the intrusion of unwanted information. regarding that event '. In this way, the Hipocampus cell region has the ability to process and store contextual information independently without interference from bad events.
Experimental mice are facilitated to express fear, then they are placed in specific contexts to follow. When scientists disabled inhibitory neurons, these mice no longer showed fear. This result demonstrates that the team succeeded in preventing the formation of fearful memories in mice.
Thereby, emphasizing the importance of the role of Interneuron cells in encrypting memory to store fear before it is passed and moved to other regions.
'Context of the event is emanating from the Hippocampus regions, moving to other areas of the brain where contexts are actually combined with events of fear'.
Understanding how neurons receive scary facts and events can help scientists help patients treat traumatic trauma after trauma.
Dr. Xu Liu, representative of the Massachusetts Institute of Technology, said: 'This research has solved the question of how Hippocampus successfully encapsulates contexts that ignore all the negative effects that are taking place. at that time. This will be a study of medical significance for many years to come. '
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