Vietnam successfully produced vaccines for cholera swine in Africa

Healthy sows are vaccinated, live with infected pigs, and remain healthy and give birth after more than two months.

At the meeting on "Solutions for use of vaccines and biological products" held by the Ministry of Agriculture and Rural Development in the morning of July 2, Prof. Nguyen Thi Lan, Director of the Vietnam Academy of Agriculture said the houses. Vietnamese science has isolated PAM cells to produce vaccines for cholera swine in Africa , studying to multiply large numbers.

Prof. Nguyen Thi Lan initially reports on research results.(Photo: Tung Dinh).

Four months ago, the Institute began to study four vaccines for cholera swine in Africa including (inactivated vaccines (tested in the laboratory), traditional deficiencies (made of virus-forming techniques , transplants of molecular biology tests), natural attenuated vaccines (screening for natural strains), vaccines using gene removal technology (ongoing research).

With inactivated vaccines, the team succeeded, isolated, selected a number of virus strains, selected vaccine production environments and identified the virulence virus strain to assess vaccine quality."The first step is to achieve good results in the laboratory scale in a narrow area , " Professor Lan said.

The research team injected a test on pig herd of Trinh Vu Trinh (Hung Yen) for 14 sows from April 18 and repeated the second injection on May 12. After 8 weeks, 13 health sows were normal, eating well and giving birth, one child died from cholera after being vaccinated 1.

Test for healthy pigs and confined with infected flocks, results show that vaccinated children are not infected.

Functional forces in Hanoi rehearse in response to African swine flu.(Photo: Ngoc Thanh).

From the experimental results, Lan confirmed that the vaccine is safe and highly protected against vaccinated pigs. However, due to the short time of research and testing, many experiments have been shortened, so Lan thinks that vaccines need to be further studied and repeated, adding more experiments to optimize the formula. , vaccine quality. Further research is needed to create better vaccines.

"The Ministry of Agriculture and Rural Development needs to provide emergency funds for research and production of African swine cholera vaccine; the organization helps the Institute assess the quality of vaccines produced to soon put them into service. export " , Professor Lan suggested.

At the meeting, representatives of many research groups from enterprises also introduced the initial results of producing vaccines and biological products that can be applied to livestock to help prevent African cholera epidemic.

Minister of Agriculture and Rural Development Nguyen Xuan Cuong said that the Ministry will direct the specialized agencies and coordinate with the Vietnam Academy of Agriculture to build a process of testing and testing vaccines in special circumstances. special of Vietnam. The Minister also directed not subjective with the results achieved, need to approach in the most creative ways to accelerate the steps, soon commercialization of vaccines to the market.

Over the past 100 years, scientists around the world have studied the production of seven strains of African pig cholera vaccine (evaluated for efficacy) from virulent virus strains. However, the commercialization of these vaccines is difficult, due to very high production costs, so prevention for pig farms with African swine cholera is not done. Every time the pathogen spreads, the measure applied is to destroy the herd of pigs.

Cholera outbreak of African pigs appeared in Vietnam more than 4 months ago and spread rapidly over 60 provinces and cities across the country. Nearly 3 million infected pigs were destroyed. At the moment, there is no sign of reduction and the risk of spreading the remaining provinces, especially in the Mekong Delta.

1. Overview of cholera swine in Africa
2. How to prevent African swine cholera