Why do bacteria cause acne only in some people?

Despite the fact that up to 80% of the world population once in a lifetime must experience nightmares called acne, and worse than acne. Of course, scientists still don't really understand the cause of this situation and how to prevent it.

But a new study has finally found the reason why bacteria that live on the skin only cause inflammation in certain people and others leave it alone.

Currently, doctors treat severe acne with one of two drugs: antibiotics or hormonal regulators such as Isotretinoin and Roaccutane.

Picture 1 of Why do bacteria cause acne only in some people?
The size of hair follicles is the answer to this problem.(Image source: gazettereview).

However, all of these drugs cause side effects. Besides, they are quite strong so they should not be taken for a long time. In some cases, these drugs still do not produce any effective effects because of the individual body structure of each person.

New research focuses on the effect of bacteria on the skin. No matter how clean our skin is, it is always covered by bacteria and this is the body's first stronghold against their invasion.

Although everyone has a lot of bacteria on their skin, some people never get acne while others try not to get rid of it.

"Normally, we live peacefully with bacteria. But at certain times, this peace is broken and you will get an infection," said University researcher Richard Gallo. California, San Diego (USA) said.

Gallo and his colleagues found that a kind of harmless bacteria that normally lives on our skin starts to cause inflammation and acne when they get stuck in a lot of sweat and oil, such as hair follicles.

But everyone's hair follicles are not the same. And that may be the reason why not everyone has acne. Some people simply have hair follicles that are smaller than others, making their habitat more stuffy and thereby making them angry against the skin's reaction.

Picture 2 of Why do bacteria cause acne only in some people?
Regular skin cleansing is not an effective cure for acne.

When trapped in anaerobic environment along with skin and hair cells, P. acnes turns sebum into fatty acids, activating inflammation in neighboring skin cells.

Usually inflammation is controlled by the body with enzymes called histone deacetylases . But bacteria will get more and more and produce more fatty acids, causing red and painful acne.

Regular cleansing of the skin is not an effective cure for acne because it has deepened in the hair follicle and closed the door with a substance called a biofilm.

"We can inhibit fatty acids, or prevent their effects on the skin," Gallo said. "I think this new method is really effective and helps significantly reduce acne status." New generation acne medications that control the fatty acids secreted by bacteria are being prepared and are expected to begin shipping to the market in the next 2 years.