Answer the mystery behind the world's most poisonous frog

The mystery behind frogs is one of the most powerful toxins in the world .

To choose the most terrifying venom of Earth is indeed very difficult, because we have so many candidates with the ability to kill dozens of people with only a few grams of toxic substances.

But if you put it on the list, Colombia's golden poison frog (Phyllobates terribilis) must be present. Batrachotoxin - batrachotoxin - batrachotoxin - though its appearance is quite harmless, can kill 10 people in just 10 minutes.

Yellow poison frog.

Batratoxin when entering blood vessels can cause salt transport channels in cells to expand permanently, thereby preventing the ability to transmit signals from the brain to the muscles. As a result, some important organs like the heart will be severely debilitated and fatal. More frightening, there is only one snake that can resist batrachotoxin, and there is no antidote yet.

The thing is, the golden frog does not create its own poison, but synthesizes it thanks to food in the wild. Evidence that when transferred into captive environments, they become really harmless like normal frogs.

The golden frog does not create its own poison, but synthesizes it thanks to food in the wild.

So the question is, how does this frog can survive carrying the most terrifying toxin in the world? This question has been a headache for experts for a long time, until the research team from New York State University (SUNY, USA) made a recent conclusion.

Specifically, the experts hypothesize that golden frogs are similar to Japanese puffer fish . This species also synthesizes tetrodotoxin with similar effects, but the body possesses a mutant amino acid, allowing them to immunity to toxins.

So, two researchers Sho-Ya Wang and Ging Kuo Wang studied the amino acids found in this frog. By using the mouse, they experimented in turn to replace 5 types of acid natural amino acids in frogs. Finally, they determined that the acid carrying the N1584T code could help mice resist completely poisoning.

The mechanism of golden frog poisoning is similar to Japanese puffer fish.

According to SUNY's team, this study is not intended to help us find antidotes. As soon as poisonous puffer fish has no antidote yet, although its immune mechanism has been found for a long time.

Instead, the purpose of the study is simply to add insights into this frog, to protect it from the effects of nature and humans. It is known that this frog is in critical condition due to the shrinking habitat.

The study is published in the PNAS scientific journal.