Application of stem cells in the treatment of chronic obstructive pulmonary disease

Currently, in the world, stem cell therapy has been studied and used to treat many different diseases, including lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, dust disease. lungs, acute lung damage.

Application of stem cells in treatment

Stem cells taken from patients have the ability to replace cells in the body, including lung, vascular, epithelial cells . These unspecified cells will help the body repair damage, Replace damaged cells with new cells and regulate the immune system, reduce inflammation.

The incidence of chronic obstructive pulmonary disease is increasing due to environmental pollution problems and smoking problems, often progressing, leading to a deteriorating quality of life. Although there have been many new drugs that increase the effectiveness of treatment for chronic obstructive pulmonary disease, however, it is still limited with cases of severe and very severe disease. Stem cell therapy is one of the new chronic obstructive pulmonary treatments that reduce symptoms and prevent disease progression. The advantage of this method compared to traditional treatments is to influence the pathogenesis by biological methods to delay or repel new injuries. Therefore, the lives of patients with chronic obstructive pulmonary disease improve.

The mechanism of treatment of chronic obstructive pulmonary disease by stem cells includes inhibition of abnormal inflammatory response, programmed cell death suppression. Currently, studies in the world are being implemented using mesenchymal stem cells obtained from adipose tissue, bone marrow for use in the treatment of chronic obstructive pulmonary disease.Mesenchymal stem cells are found in the bone marrow, adipose tissue, pulp and umbilical cord, with the ability to replicate, the ability to move to the damaged area and the ability to regulate immunity.

Application in the world medicine regeneration medicine confirmed that mesenchymal stem cells are the type of stem cells with high safety, do not cause serious side effects after transplantation.

Clinical picture in chronic obstructive pulmonary disease.

And the initial results

The results of the studies show an improvement after stem cell therapy in patients with chronic obstructive pulmonary disease on the following issues: Reduced abnormal inflammatory response; Reduce difficulty breathing; Improve exertion capacity, restore activity, enhance vitality; Improve sleep; Reduce the number of hospitalizations / exacerbations.

With the initial successes of several studies on stem cell treatment for patients with chronic obstructive pulmonary disease, along with significant advances in medicine around the world in cell technology development The original, many scientists are continuing to carry out larger-scale studies to demonstrate the role of stem cells from adipose tissue and bone marrow in this pathological treatment.

Research on stem cell treatment for patients with chronic obstructive pulmonary disease in Vietnam is a new direction with many prospects. In 2015, Van Hanh Hospital initially researched and evaluated the role of stem cells from adipose tissue itself in the treatment of chronic obstructive pulmonary disease, research results have not seen any adverse events related to transmit stem cells themselves from adipose tissue. Therefore, it is necessary to conduct many studies to find an effective new method for patients with chronic obstructive pulmonary disease who do not respond to other optimal treatments and are a prerequisite for further studies in the treatment of chronic lung diseases. Stem cell therapy in chronic obstructive pulmonary disease is promising therapy in the present and in the future.

The upcoming Bach Mai Hospital will implement a state-level scientific research project "Research on the use of autologous stem cells from adipose tissue and bone marrow in the treatment of chronic obstructive pulmonary disease" has been approved by the Ministry of Science Study Technology approval. We hope this will be a promising treatment for patients with chronic obstructive pulmonary disease. However, the most important is to prevent the disease by not smoking tobacco pipe tobacco, reducing exposure to dust, environmental pollution .