Because of possessing many preeminent genes, can humans live for hundreds of years?
Among primates, humans have a relatively high life expectancy. Up to half a million people around the world live longer than 100 years, and that's because of the mutations in human evolution.
Scientists have discovered 25 types of genetic mutations that can help us live longer and meet our relatives for many years. From this finding, researchers hope to come up with a way to improve health and increase life expectancy for a few more years.
People are carrying a preeminent set of genes?
In the group of primates, gorillas and chimpanzees who are very close relatives of humans, but only live for less than 60 years is the maximum. Life in animals has lasted a lot during evolutionary history. The ancestors of humans and monkeys had an average life expectancy similar to each other 30 million years ago.
Mutations in the genome have made humans improve their lifespan and live much longer than our ancestors millions of years ago.(Photo: CNBC).
Previous scientific circles have proposed many theories about the difference in life expectancy between humans and other animals, such as the relationship between metabolism and the risk of cell aging of animals is different. each other, mutations make the aging process less active .
The theory of pleiotropic was proposed half a century ago by biologist George C. Williams of the United States has shown that the phenomenon of genes that are too healthy or unhealthy also affects the body more or less. Genomes in different animals are different, leading to differences in life expectancy for each species.
But the hypotheses set in the past have not had any definitive evidence. So the team of scientists from Spain's Evolutionary Biological Research Institute looked for mutations in evolution in primates to see if the genome that humans are carrying is a genome. Superior or not.
25 genetic mutations make people live longer
By analyzing the average life expectancy, maximum life expectancy and characteristics of living conditions, evolutionary history as well as many other factors, the team has identified only three species of modern primates that live long. more than their ancestors, are human and two other monkey species.
These 3 primates during the past were once "standard" for other species to evolve in order to have a longer lifespan. After analyzing the differences in different amino acid sequences, the team found 25 genetic mutations that made each species develop in a distinctly different direction.
"This finding suggests that these differences in each species' genome have led to an extension of the life of each species," said researcher Arcadi Navarro from the Institute of Evolutionary Biology.
Jeanne Calment, a French woman, is the oldest person in the world, now she is 122 years old but still living well.(Photo: Wikipedia).
These mutant genes are primarily linked to cardiovascular health, including wound healing and blood flow that helps blood clot faster. This discovery surprised the scientific community, clearly showing that humans have evolved to live longer through generations.
'The results of this study are very meaningful to us, one of the most valuable mutations is the rapid coagulation mechanism, which helps us not to bleed much and lead to casualties if left for a long time , ' The study's lead author, Gerard Muntané, is currently working at the same agency, sharing.
The rapid coagulation mechanism is not only useful in the early years of our lives, but also affects our whole life, which considers the right and wrong of the pleiotropic theory proposed by Williams in the last century.
This study focused on finding protein products of genes, meaning that there are many other genetic mutations that are not mentioned. 25 mutations of this gene are only a small part of the answer to the longevity of humanity, in the future the scientific world will learn more deeply.
However, this discovery is of fundamental value, as the first step to show the difference between humans and other species, especially primates, to find the reason for the age difference. life. From this research, the scientific community will overcome the limitations to help people live longer with technology.
The study was published in Molecular Biology and Evolution.
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