Control the sperm's gene
Scientists at the Australian National University have discovered the mechanism of activating genes involved in differentiating cells. Thus, it is possible to cure infertility in men, said Nature Structural and Molecular Biology .
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While studying changes related to cell formation, a group of researchers led by Professor David Tremethick discovered an epigenetic agent, protid H2A.Lap1.
H2A.Lap1 has the function of regulating the gene activity of sperm.
This epigenetic agent affects DNA when transferring genetic information.
It has been shown that H2A.Lap1 functions to regulate the sperm activity of the sperm, acting directly on chromatin at the site of the detection and comparison of genetic information.
With that function, H2A.Lap1 will 'turn on' this gene, 'off' the other gene, and play a major role in fetal development and sexual maturation.
Professor Temethick said: 'By inventing a new way to activate genes, we can better understand how the differentiation of cells in the fetus takes place. This is very practical. In the future, it could lead to new methods called 'epigenetic genetic methods' to treat male infertility . '
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