Detection of breakthroughs in female ovaries

The ovaries of women have the ability to produce new eggs in the reproductive age, according to a study published in Nature Medicine.

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Previous medical studies suggest that women are born with a fixed number of eggs throughout their lives.

However, scientists have recently discovered a new type of stem cell in the ovary, when grown in a laboratory that has developed into young egg cells. Tests on mice showed that the young egg cells, when removed from the ovaries of mice, could develop into eggs capable of fertilization.

Picture 1 of Detection of breakthroughs in female ovaries
Sperm is surrounding an egg (400 times magnification).

Scientists conducted experiments to separate stem cells from perfectly healthy ovaries donated by a woman. The stem cells are then fluorescently fluorescent and transplanted into human ovarian tissue, then transplanted into female mice.

Within 1-2 weeks, fluorescent dye stem cells developed into immature egg cells; because they are still fluorescently dyed, they are easily distinguishable from existing egg cells.

More research will be needed to test the ability of these eggs to survive. However, the research leader, Jonathan Tilly, Director of the Venter Center for Reproductive Biology (USA), believes this step "will open up the opportunity someday, we can move forward." to reach the number of eggs without limits for humans ".

The scientists also found that the number of stem cells in the ovaries is very rare, only less than 1% of the total number of oocytes in the organ. This may be the reason why this type of cell has been "conceded" by scientists for many years.

In experiments with mice, it was also found the presence of sperm cells in old mice with degenerate spermatogenesis. When these cells are implanted in the testicles of a healthy mouse, they immediately "wake up" and begin to develop sperm as normal.

Therefore, the researchers believe that, in males, degenerative genitalia may not be due to the loss of these stem cells but the degradation of the "house" containing them. Since then, Tilly's group has argued that there may be a similar phenomenon in women.