Develop effective drug detox vaccine within 6 months to 1 year

This drug is the aftermath of rock drug, favored for its cheap price, easy to camouflage and strong effect.

A team of researchers at the University of Arkansas Medical School, USA, says they are developing a vaccine for drug addiction. This vaccine is administered once and lasts for 6 months to 1 year, targeting patients with synthetic cathinone.

Synthetic cathinone is a notorious drug, often referred to as 'bath salts'. As its name suggests, this drug is made into white or pink crystals like regular bath salts.

Synthesis of Cathinone appeared with many names such as Flakka, Ivory Wave, Vanilla Sky . is a cheap drug trend followed by stone drugs. Even more dangerous than stone, people using bath salts can be psychotic, strong hallucinations leading to violence and very aggressive.

Their behavior is compared to zombies. There have been accusations of people using offensive and carnivorous bath salts in the United States.

Bath salts are prepared into white or pink crystals like regular bath salts.

Research by the Arkansas Medical University has been reported this week at the Experimental Biology Conference, bringing together more than 14,000 scientists. In it, scientists presented the process of developing a vaccine that prevents the effects of methylenedioxypyrovalerone (MDPV) and alpha-pyrrolidinovalerophenone (alpha-PVP) . These are the two types of synthetic cathinones commonly used as bath salts.

'When injected, the vaccine will activate the immune response, causing the body to produce antibodies against drugs,' said Samantha Mcclenahan, lead author of the study at Arkansas Medical University. 'When drugs are abused, these antibodies will combine with blood drugs and limit its distribution to vital organs, thus reducing side effects and "satisfying" effects. of medicine '.

In experiments with mice, scientists found that vaccines actually helped them secrete antibodies associated with MDPV and alpha-PVP. These antibodies do not affect other harmless targets such as neurotransmitters and unrelated drugs, including some over-the-counter medicines.

Compared to untreated mice, the vaccine shortened and delayed the stimulating effect of increasing MDPV doses on their movements. The effects of the vaccine continue to be monitored, but it has been effective for at least 3 months, until the time this study was reported.

The bath salts contain synthetic cathinone types, which mimic the effects of natural cathinone in the plant, often grown in the Middle East, the Arabian Peninsula and the African region. This drug is the aftermath of rock drug, favored for its cheap price, easy to camouflage and strong effect.

Bath salt producers often change its formula to bypass security agencies. However, the new research team says they can develop vaccines that work with a variety of refined bath salts, providing broader protection effects.

And in addition to bath salts, they believed that their technique could be used to develop vaccines for other drugs. Prior to this study, Mcclenahan's lab used to develop vaccines and antibodies for PCP and methamphetamine, a component of stone drugs.

Currently, the research team at the University of Arkansas Medical School is continuing to examine the long-term effects and safety of the new vaccine on mice. They think their drugs can be effective for at least 6 months to 1 year.