Escape from myocardial infarction with the injection containing the 'discarded' thing

US researchers reversed the damage caused by myocardial infarction by injecting patients with seemingly discarded cells.

After serving as a source of life for babies in the womb, the placenta is often discarded when the baby is born. However, scientists from the Icahn School of Medicine in Mount Sinai (New York - USA) picked up this discarded imaginary part, extracted the Cdx2 stem cells , injected them for the experimental mice that had gone through. myocardial infarction and witnessed a spectacular recovery.

An injection containing stem cells from the placenta can save many heart attacks and heart failure - (illustrations from the internet).

When entering the body, these placental cells have made an incredible "overhaul" on the heart that has been severely damaged by a heart attack. They repair the damaged areas, bringing the heart back in time to when the accident has not yet occurred.

With that ability, these stem cells also have the potential to treat patients with severe heart failure, especially those with only heart transplantation to maintain life. It will be great news because the source of donor organs is inadequate, while the world has an estimated 23 million heart failure patients. And myocardial infarction has always been considered one of the leading cardiovascular and fatal sequelae.

Cardiac muscle cells are a cell type with a copy rate of only 0.5% per year - too slow to repair any significant damage by heart attack or heart failure. Instead, dead cells are replaced by thick, hard scarring, which causes the parts of the heart to stop working. Meanwhile, placental stem cells entering the body will produce true heart cells, abundance of vitality, replacing the damaged cells.

Dr Hina Chaudhry, medical director for cardiovascular regeneration at Icahn School of Medicine in Mount Sinai, said they isolated similar Cdx2 cells from human placenta and will soon be tested on humans.

Previously, there were studies based on embryonic stem cells and they have been shown to form heart cells, serving the same purpose. However, using embryos encounters many ethical issues and feasibility.

"Meanwhile, the placenta is frequently discarded all over the world and therefore, it is almost an infinite source," said Dr. Chaudhry.

The research has just been published in the scientific journal Proceedings of the National Academy of Sciences.