Find a protein that makes women difficult to give birth

Scientists at the University of Newcastle, UK, said that in modern society, more and more women when they reach the age of 40 are just starting to want to give birth, thus causing many problems about childbirth.

The results of the study, published in the latest issue of the issue of Contemporary Digital Biology, show that older women have an unusual problem of childbirth that may have a relationship with aging of a kind. protein .

Scientists conducted a comparative analysis of egg production at different ages of laboratory mice.

The results showed that the function of cohesin protein in mice will gradually lead to aging along with increasing age. Cohesin protein has chromosomal binding effect.

Usually there are two sets of chromosomes in somatic cells and eggs during formation need to have the cohesin protein to perform the " cut off " task. Therefore, this weak working protein causes abnormal numbers of chromosomes in the egg, which can cause problems such as infertility, miscarriage or birth defects.

Dr. Mary Herbert, in charge of the research team, said the mice had an age equivalent to that of a 40-year-old.

The function of cohesin protein has decreased markedly, often causing abnormal chromosomal activity and reproductive problems.

This suggests that the aging of cohesin protein may be the underlying cause of a decline in the reproductive function of women in their 40s .

This finding has important implications for finding new ways to treat diseases related to childbirth in older women.