Find the drug that is capable of 'eradicating'

This drug can pull HIV viruses hidden deep in the body and destroy them in blood vessels.

Find a drug that can 'eradicate' HIV

Recently, a team of UC Davis University of Medicine (USA) has published a new discovery in PLoS Pathogens, which emphasizes that HIV can be eradicated in the human body by a kind. anticancer drugs.

The most effective treatment for HIV is antiretroviral therapy (ART), but this method can only kill the HIV virus in the blood vessels but cannot reach the internal 'HIV drives'. body.

Current anti-exposure drugs cannot kill HIV virus lurking in the body

The danger of these 'HIV drives' is reflected in the case of a girl in Mississippi, USA. From birth, this girl has been using anti- exposure drugs. Although for 2 years after using the drug, she was confirmed negative for HIV tests, but the deadly virus remained hidden in the tissues of her body without being completely destroyed.

The "radical elimination" strategy that new scientists have come up with is considered the key to HIV treatment , which is to use drugs to wake up HIV viruses that are still hiding in the body, and when they invade In blood sugar, other drugs will destroy them.

The drug used by the UC Davis Medical Group is PEP005, one of the key ingredients in the treatment of skin cancer . They tested the drug on cell cultures in the lab and on part of immune cells removed from 13 HIV-infected patients.

The results showed that PEP005 'has a high likelihood of re-activating HIV virus hiding ', and the drug is considered a pioneer in the current war on HIV.

Dr Satya Dandekar, who participated in the study, said: 'We are excited to identify a prominent candidate for the reactivation and elimination of HIV, especially when the drug has been approved and allowed for use on patients'.

PEP005 was identified as a potential candidate for the fight against HIV.(Illustration)

However, so far, the drug has not been tested in HIV-positive patients, and researchers hope it will soon be included in clinical trials.

Professor Sharon Lewin of the University of Melbourne said the result was 'very interesting ' and marked 'an important step in finding new ways to eradicate the body's hidden HIV virus'.

"This work has found a new drug that can eliminate long-term HIV infection in the body, although there is still a lot of work to do to verify its ability in the body, " Lewin said. patient'.

The professor explained further: ' Although PEP005 is an FDA-approved drug, scientists have to prove that it is safe to use in HIV-infected patients, and this will lose quite a bit. a lot of time'.