Foot calluses can be a sign of an extremely dangerous disease

Foot bottles are very thick, dead skin areas formed by skin rubbing too much with hard objects. However, not only is it aesthetics, it can also be a sign of a very dangerous disease.

In general, having bottles is no harm to the aesthetic problem, so few of us care about it. Only according to a recent study, it seems all of us are wrong, because these calluses can be a sign of an extremely dangerous disease.

Bottles that are too thick, too much can be a sign of esophageal cancer.

Specifically, research from Queen Mary University (London, UK) suggests that hand calluses, foot bottles are closely related to esophageal cancer . Accordingly, genes thought to cause esophageal cancer are also the cause of our calluses on hands or feet.

According to the team, the cancer-causing gene , iRHOM2, also has the ability to control Keratin - a type of protein in the outermost layer of the skin, the main culprit producing calluses.

In mouse experiments, individuals with the gene iRHOM2 had skin under abnormal thick extremities. In humans, it is the skin layers under the soles of the feet and hands.

Overall, research has the potential to create a new diagnostic and therapeutic approach for patients with esophageal cancer. However, the team also recommends that we should now pay more attention to the more obvious signs of the disease, such as finding it difficult to swallow certain foods such as vegetables, bread, meat . Chest pain, fatigue, easy vomiting, frequent throat sputum are also not to be missed.

Currently, esophageal cancer is ranked 11th in the list of the most killer causes in the United States. In 2016, the country had 16,000 people died of the disease.