Genes decide 'women's life expectancy'

Scientists have found genes that determine when to start and end a woman's reproductive function.

This finding may lead to new treatments to treat the body's fertility disorders and related diseases such as breast cancer or osteoporosis.

The independent study of five groups of British, American, Icelandic, Dutch and Australian scientists published in the May 18 issue of "Nature Genetics" led to the above conclusion.

During the study, scientists analyzed data on the most common variants of DNA among thousands of women living in different parts of the world and compared them with age and age data. the start of a certain reproductive period.

4 out of 5 scientific groups have demonstrated that DNA variants in the LIN28B gene region lead to changes in the start of the first menstrual period.

This gene is responsible for synthesizing proteins and in turn, this protein controls the amount and proportion of other proteins synthesized by the cells of the body. However, how the LIN28B gene affects the start of the first period is still a mystery.

A series of previous scientific studies have shown that the LIN28B gene has somehow affected human growth. So scientists argue that their findings partly explain why early puberty girls are more modest in height than girls with the first menstrual cycle late.

Meanwhile, Dutch scientists have discovered genes related to menopause. Most women go through this period between 40 and 60 years old.

The team of scientists from the Netherlands eCODE Genetics company discovered that in the human genome, genes that determine the menopause begin sooner or later than 2 years.

However, according to scientists, it is possible that genes found to play a more important role in the development of the body, not just the time of menopause or the first period.

A group of scientists at the Epidemiological Research Council of Cambridge (UK) Medical Research Council found DNA variants, affecting the first period, located in chromosomes near genes. The other is related to breast development in girls and a broken voice in boys.