Interaction should be avoided when taking medications

Do not use grapefruit juice to take medicine. Cyclin drugs must be used after drinking milk or crab soup, morning glory for 3 hours.

Master, Doctor Than Ha Ngoc The, head of the geriatric unit, Hospital of Ho Chi Minh City University of Medicine and Pharmacy, said that using drugs can lead to drug interactions that increase or decrease the effects of drugs and can cause poisoning . The drug may also interact with food, herbal products, alcohol and other pathologies available.

During the course of medication, some interactions may be noted, especially in the elderly:

Drugs and grapefruit juice

Grapefruit juice affects many drugs.(Photo: quangnam)

Grapefruit water affects drugs very much. Grapefruit juice has the effect of inhibiting drug-converting enzyme in the intestinal wall and liver, increasing the pharmacological effect of some drugs such as antihypertensive drugs that suppress calcium channel, stalin drug reduces blood fat, antiarrhythmic drugs, and tranquilizers god benzodiazepines . So it is necessary to limit the use of grapefruit juice when taking some of the above medicines.

Medicine and milk

Calcium and milk will combine with cyclin antibiotics, reducing drug absorption. Cyclin drugs (tetracyclin, hexacyclin) must be used after drinking milk or crab soup, morning glory for 3 hours.

Food or gastric juice may increase or decrease absorption, or increase drug destruction, leading to an increase or decrease in the effect of the drug. Depending on the type of medicine, it should be taken between, right after or away from the meal.

Drug and drug interaction

Antacids, sucralfate, iron, calcium supplements can reduce the effects of tetracycline and quinolone antibiotics. So do not use these groups of drugs together.

Some drugs inhibit or increase metabolism of drugs with narrow treatment windows. Some kidney purification inhibitors, competitive inhibition of renal tubular secretion of other drugs . can reduce or increase the effect and cause toxicity.

Some medications when taken together can cause many side effects.(Photo: medical)

There are some drugs that change the response of other drugs and cause side effects. At the same time many anticholinergic drugs can cause delirium, urinary retention, and constipation . Taking beta-blockers together with verapamil may cause more bradycardia. Using at the same time many antihypertensive drugs may cause blood pressure to drop significantly. Concurrent use of several drugs such as benzodiadepine, tranquilizers, narcotic drugs, antidepressants, tranquilizers . can cause drowsiness and falls.

Drug interactions with the disease

Drugs that can affect disease or disease can affect drugs. Anti-inflammatory drugs can make stomach ulcers worse, can cause gastrointestinal bleeding. Anti-emetic drugs (primperan) may increase symptoms of Parkison disease. Kidney disease causes slow elimination, easy to accumulate causing poisoning.

According to Dr. Ngoc The, to make the medicine safe and effective, attention should be paid to the use of the drug when absolutely necessary as prescribed by the doctor. Do not arbitrarily increase or decrease doses, add or replace drugs. Watch and note abnormal disorders that may be caused by drugs.