One more step: Cloning of primates

Technological breakthroughs have allowed British scientists to replicate 12 embryos from mature monkeys for the first time.

The study was led by Shoukhrat Mitalipov, a Russian scientist at Oregon's National Primate Animal Research Center - at Beaverton, England.

First cloned embryo

Dr. Mitalipov pioneered in finding a new way to control primates' eggs during cloning. This process involves combining eggs with kernels separated from a skin of an adult primate.

Every effort in embryo replication to serve research has been constrained by technological problems and debates about the results of lies and ethical research. But the new technology of the Oregon group promises a revolution.

For the first time, scientists can create clones that exist independently from an adult primate. In this case, they used 10-year-old male brown monkey (rhesus macaque monkey). Research results will be reported by the research team at the end of November.

British scientists cloned 12 embryos for the first time
mature monkeys. ( Photo: www.grg.org )

The team also demonstrated that they could extract stem cells from these cloned embryos. In the lab environment, they can control and make embryonic cells grow in mature heart cells or nerve cells.

According to experts, this is the breakthrough they are expecting. Until now, people still felt there were quite a few insurmountable barriers in forming human embryos from mature primates - including humans.

This new research result is not always welcomed by organizations. Many cloning organizations claim that the new technique of primates' egg manipulation will lead to new - and disruptive - human embryos for research purposes.

In the UK, it is illegal to transplant any human embryo into a woman's uterus. However, many people still fear that the success of cloning from adult skin cells will increase the chances of having a baby by cloning.

In 2004, South Korea announced that its scientists succeeded in creating the first human embryo. But in 2006, the results of this study were rejected when the project manager, Mr. Hwang Woo-suk, was convicted of fraud.

There is only one case of human embryos recorded on paper, but this embryo died after a few hours and did not produce stem cells. Meanwhile, this primate team has implanted 100 human embryos into the uterus of about 50 female brown monkeys. However, no one baby monkey was born.

A senior scientist in this research group said that it was merely unfortunate. In order to create Dolly, the first animal cloned in the world, it takes 277 times.

Dr. Mitalipov said he could not make any comment until the study was published in the journal Nature. But in a recent colleague meeting, he revealed he created two " batches " of stem cells from 20 cloned embryos and test methods that proved to be true from cloning.

Dr. Alan Trounson of Monash University - Australia said Dr. Moripov's findings represent breakthroughs after long years of waiting . Despite a great deal of effort, no scientist has been able to produce cloned human primates from mature cells, while cloning of dozens of other animals has been successful.

According to Dr. Don Wolf, former head of Oregon National Primate Research Center's lab, the new technology is based on microscopic microscopy technology, which does not use ultraviolet light and dye. These technologies can damage primates' eggs.

" In the early days, we tried to use all of these technologies in monkeys and absolutely did not know which ones destroyed the eggs. Therefore, one of the keys to success was to eliminate every step of the research process. Currently, we can clone monkey embryos more often, or at least we have created a routine procedure . to study primate replication , "said Dr. Wolf said.

This new technique is based on microscopic microscopy technology, which does not use ultraviolet and dye light
(can damage primate eggs). (Artwork: H. Cat _ Vietnamnet)

Cloning history

Monkey cloning technology basically has the same process as the cloning of Dolly sheep. The nucleus of a healthy, unfertilized egg is replaced by another kernel from an animal's mature skin cell.

With careful calculation of time and the use of electrical impulses, an embryo can be created. The embryo now carries the genetic gene of the skin donor. One can transplant embryos created in this way into the animal's uterus to create clones.

" Human cloning " is considered illegal in England and many other countries. However, this replication method has been applied in some animals. Many cattle have been successfully cloned. The first attempt by anthropologists was to clone a clone of the nearly extinct bison, named Noah. Noah was cloned in the US in 2001, but died after 48 hours of birth.

The horse named Prometeap was born in Italy in May 2003 ( Photo: BBC )

Previously, scientists cloned mice. Cumulina is a familiar brown house mouse. Cumulina was cloned from adult cells at the University of Hawaii in 1997. The mother mouse lived to adulthood, giving birth to two baby mice, before leaving her life in May 2000.

The horse named Prometea, the first cloned version of the Italian-born horse in May 2003. And the cloned cat CopyCat was born in 2002, in Texas. For a normal male cat, CopyCat was the mother of three other cats in September 2006.

And the dog Snuppy, has been cloned in Korea. The doubts about Snuppy's authenticity have been dispelled after the results of DNA genetic testing. The same team created two cloned baby wolves, called Snuwolf and Snuwolffy. Talking about dogs, people also cloned three Afgan dog breed dogs, named Bona, Peace and Hope.

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