Paracetamol with caffeine: Dangerous!

If Paracetamol (acetaminophen) is used, common painkillers with alcohol will harm the liver, but a new study in the US suggests that taking paracetamol with caffeine (a substance found in coffee) can also damage the liver. .

It has long been known that the dangerous and potentially fatal consequences of combining alcohol with acetaminophen - or paracetamon, one of the common painkillers. However, according to a new study by the University of Washington, Seattle, combining large amounts of caffeine with acetaminophen can also be harmful.

Not only drinking caffeine while taking dangerous new drugs, but some treatments that combine caffeine with acetaminophen such as menstrual disorders, arthritis and many other conditions can also impair kidney function. High blood pressure and stroke.

Dr. Sid Nelson, of the University of Washington, and the team said acetaminophen and caffeine act on an important enzyme in the human body that is involved in liver detoxification.

Chemical formula and molecular structure of Paracetamol.(Photo: 3dchem)

Research has shown that caffeine triples N-acetypl-p-benzoquinone (NAPQI) 3 times, a poison produced by enzymes during acetaminophen reduction.

NAPQI also causes liver damage and makes the interaction between alcohol and acetaminophen harmful to the body. Tests on mice given acetaminophen have also shown that high levels of caffeine can damage the liver.

Talking about his new research, Dr. Nelson said the purpose of the study was to warn people about the potential danger between combining paracetamol and caffeine. However, you do not have to stop taking acetaminophen or caffeine, but it is important that you carefully adjust their dosage when combined. Especially, if you drink alcohol, you must be even more careful.

The best thing is to adjust the dose when using coffee and paracetamol ( Collective illustration).

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