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Scientists have made short and strong electric shocks to break the outer shell of sperm and then inserted a gene editing tool to eliminate birth defects and congenital diseases.
The above work was presented at the annual meeting of the European Human Reproduction and Embryology Association. The goal of the work is to fix human DNA from the period of being a sperm in the father's body, thereby eliminating irreversible genetic diseases and birth defects.
Electric shock will help scientists put gene editing tools safely into sperm - (photo: NEW SCIENTIST).
Interfering with sperm DNA is quite difficult because these warriors are fragile and can die from tricks. The team of scientists from Weill Cornell University of Medicine has found a way to solve this problem with short and powerful electric shocks.
An electrical pulse of up to 1,100 volts passed into the sperm in a very short time (only 0.02 seconds) will help scientists temporarily break down a portion of the sperm's outer shell, enough to bring the system into Fix famous genes that interfere with DNA.
This public intervention targets more than 10,000 single gene disorders that can be passed on to the next generation in men, including genetic disorders that can cause sickle cell disease, cystic fibrosis, muscle disorders . These are the current incurable diseases, the child can only wait for death.
Dr. Diane Choi, head of the study, said they had initial success on some human embryos and will continue to expand research to prove its safety, before creating a real person. . However, research leads to much controversy. Many scientists worry that the work will be used to repair DNA and to produce "superman" babies instead of merely eliminating incurable diseases.
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