There will be no babies born prematurely thanks to the new remedy

Scientists have provided evidence of how to safely insert drugs into the fetus to help prevent premature birth and treat common complications during pregnancy.

It is estimated that up to 10% of pregnancies have serological complications leading to premature birth and diseases such as pre-eclampsia, which is caused by a history of high blood pressure and water retention disease. seriously affects the development of the baby.

Many complications that occur during pregnancy are related to the failure of the placenta by not providing enough nutrition, or the internal environment becomes too harsh for the fetus.

And also because of this extremely sensitive environment, so far there have not been many methods implemented. For the first time, a group of international researchers have found a way to bring straight pills to the placenta to help the placenta actively enhance its functioning.

Researchers have achieved this by treating the placenta like a tumor.(Artwork: Leptospira / Shutterstock.com).

Researchers have achieved this by treating the placenta like a tumor. "The placenta is like a well-controlled tumor. They grow quickly, producing growth hormones and destroying the immune system," said lead researcher Lynda Harris of the University of Manchester in England . of pregnant women ".

She also added: "Cancer studies focus on finding ways to deliver drugs to destroy cancer cells without adversely affecting other organs of the body. We have an idea about Whether it can affect the placenta according to the same mechanism with the tumor, then we can take different drugs to improve the placental function, thereby treating complications in pregnancy ".

Cooking this idea, Harris and the team decided to consider how the placenta would react to two cancer-specific peptides called CGKRK, iRGD , which are amino acid sequences that act like capsules. very small, take medicine to cancer cells.

The team experimented on pregnant mice and found that similar to how peptides work with tumors, they may also target only the introduction of the drug into the placental tissue and provide growth hormone. to improve the function of organs.

While growth hormones do not seem to affect the fetus of normal-sized mice, in contrast, abnormal fetuses due to damaged placenta are shown to develop in response to increased hormones. Chief.

When testing human placental tissue peptides, they showed association with cells and entered cell membranes. From here the same results can be tested replicated on people in the future.

There are currently no drugs available for placental complications.

The team also reported that no trace of residual drugs was found in the fetus or in the mother's body after the duration of the drug's effect.

They also said in advance that a treatment problem could be dangerous for mothers diagnosed with cancer. Because peptides will not know what targets are needed - the placenta or the tumor, but the team said they will overcome this with appropriate screening methods.

Currently there are not any drugs that can be used in cases of non-active placenta complications developing in the wrong direction. Instead, the doctor must give birth early and hope no problem occurs. However, the risks associated with preterm birth are significant including not only the risk of infection and cerebral palsy but also heart disease and diabetes.

Harris said: "Over the past twenty years, only one drug has been approved for use during pregnancy. By developing this method, we hope to open the possibility for new drugs to Use safely in the treatment of common and serious complications during pregnancy ".