5 gene variants related to prostate cancer

The US-Sweden team of scientists has just published the results of the scientific work, saying they have found five gene variants that are closely related to prostate cancer.

Five new gene variants are LEPR, RNASEL, IL4, CRY1 and ARVCF , all of which are single nucleotide nuclei or variants such as SNP, DNA are linked to prostate cancer.

Research leader, scientist Janet Stanford of Fred Hutchinson Cancer Center, said they chose to study the SNP gene variant because it plays a key role in biotransformation related to the development of the disease. such as infections, steroid-hormone production and metabolism, gene recovery DNA .

During the study, scientists analyzed DNA in blood samples from 1,309 prostate cancer patients between the ages of 35 and 74, and they found 22 SNP variant genes that are confirmed to be closely related to deaths from this disease.

Further investigation into the 22 SNP gene variants of the patients with this disease group in Sweden have the same reference parameters, the researchers selected five variants of SNP gene that have a serious impact on the process. disease development.

Every year, prostate cancer kills more than 32,000 male patients in the United States. Each year there are more than 240,000 new cases. The cost of treating this disease in the first stage is up to 3 billion USD / year.