Detects compounds in tropical plants that cure pancreatic cancer

German and Japanese scientists have discovered a compound called alkaloid alkystrolikokin E3 in tropical plants helps destroy pancreatic cancer cells and prevent them from metastasizing.

According to Medical News Today, scientists have discovered a new compound that can treat pancreatic cancer - one of the most malignant cancers. This type of cancer is very difficult to treat (cells survive in the most unfavorable conditions) and cause high mortality rates. According to the American Cancer Society (ACS), the 5-year survival rate for people with early pancreatic cancer is only 12-14%.

Compounds in Ancistrocladus likoko woody vines help prevent cancer cells from communicating and spreading.

Pancreatic cancer cells can take all the oxygen and nutrients from the environment, using them to actively spread by activating the molecular pathway Akt / mTOR . This is the signal path to help cells communicate with each other.

Recently, German and Japanese scientists have discovered an anticancer compound - alkaloid ancystrolikokin E3 - discovered in the woody plant Ancistrocladus likoko in the Congo rainforest, preventing cancer cells. Communication letters and spread.

Published in the Journal of Natural Products, the scientists explain that this compound causes serious changes in the morphology of cancer cells, causing them to die. This compound kills cancer cells by inhibiting autophagy and Akt / mTOR molecular pathways, which help cancer survive in the harshest conditions. Moreover, this compound prevents cancer cells from metastasizing.