Find out how to replace weak old cells in the human body

Aging is no longer a man's nightmare, when scientists recently did a miracle. A remarkable study has found a way to remove cells that no longer function well in our bodies.

The study was done by a team of scientists from Caltech and UCLA. The study led to the development of a nip-n-tuck-style process (squeezing and pressing two surfaces or points tightly), which will help reverse and slow down the aging process. The experiment is aimed at altering the DNA inside our mitochondria - which is considered the "battery" of cells. But now, in the process of creating, the Caltech team - UCLA has found a way to manipulate genes, so that they break down and remove altered DNA, and reconstruct cells.

This process is a twisting of the natural process of available material, called self-eating . Through self-actualization, cells can classify mitochondria (mitochondria containing ATP and enzymes involved in cellular metabolism) with dysfunction. In addition it also has the ability to clean up so that the replacement becomes safe for the health to the best possible level. Now this process is a hot topic - the truth about this self-study has won the Nobel Prize this year.

Mutated mitochondrial DNA can be removed.(Photo: Getty Images).

But before Caltech - UCLA's study was announced on Monday, there was no clear thing. People wonder if this process, can also promote selective removal of mutations, in aging DNA? The accumulation of mutant mitochondrial DNA throughout life, is thought to contribute to aging and degenerative diseases of old age such as dementia, paralysis, and disease causing excess meat. These diseases are related to the loss of muscles and the frail and vulnerable body.

Inheriting deficiencies in mitochondrial DNA is also linked to many conditions found in children, including autism."We know that the increase in the rate of mutant mitochondrial DNA causes premature aging. It is also true that mutant mitochondrial DNA accumulates in major tissues such as neurons and muscles, losing organs. "When we get older, we think that if we can reduce mutant mitochondrial DNA, we can slow and reverse the aging process," said Bruce Hay, a professor at Caltech.

In order to test your method effectively, the team used the popular fruit fly variety. They focused on mitochondrial DNA in the fruit flies' muscles, as this is one of the most energy-intensive tissues in the animal kingdom. Like humans, the flies' muscles exhibit some clear signs of aging. Fruit flies and people with similar genetic diseases.

In the experiment, fruit flies are genetically designed so that 75% of mitochondrial DNA is mutated early. They then intentionally increased the activity of genes that promote phagocytosis. Accordingly, the fraction of mitochondrial DNA mutated in fruit fly muscle cells dropped surprisingly. A special gene, called "parkin" , reduces the fraction of mitochondrial DNA mutations from 76% to 5% when it is overly suppressed. Another gene, called "Atg1", reduces the fraction by 4%.

Both genes appear to be poorly functioning in the elderly and people with genetic diseases such as paralysis. " Reducing the yield of genes will completely eliminate any deficiencies in these cells. We will also store them so that people always have a young, energetic state." Professor Hay said.

"The experiment is seen as a clear illustration of the extent to which mutant mitochondrial DNA can be reduced in cells, by gently" twisting "normal cell processes. create a future where we can control and eliminate harmful mitochondrial DNA from the brain, muscles and tissues, which will help us retain our intellect, flexibility and body health. more " , Mr. Hay added.