High salt intake can lead to multiple sclerosis?

(scienceinfo.net) - Findings from early laboratory studies suggest that the amount of salt in our diet may be related to boosting the body's immune system to rebel against them. we lead to diseases like multiple sclerosis (MS).

Several groups of scientists simultaneously published data in the journal Nature that shows this connection.

Salt can activate part of the immune system, the system that helps protect the body.

Experts say the findings are interesting and reliable, but not a cure for people with MS.

Defenses to protect the body against infection of the body can be seriously harmed, causing infections to exist on the body and leading to self-acquired diseases such as type 1 diabetes, arthritis Low form and multiple sclerosis.

Genetics is thought to be a factor that increases the risk of the above diseases, but the world around us also has a big impact. One of the leading theories that explains the cause of multiple sclerosis is viral infection, but smoking and vitamin D deficiency can make it easier for them to develop.

Now researchers believe they have the first evidence that salt in our diet can also contribute to the rise of disease.

Research groups at Brigham and Women Hospital and Broad Institute of MIT and Harvard are investigating part of the immune system that has been linked to immunodeficiency disease.

'We were all really surprised to see how the change in dietary salt levels could have such a profound effect.' The conclusion of Professor David Hafler of Yale University. .

They wanted to know how 17 T-cells were produced.

An in-depth analysis of the complex chemicals needed to form a supportive group of 17 T-cells is closely related to cell control and reverse engineering - identified. an important gene. But this gene has been seen before.

The amount of salt in the diet contributes to the rise of disease

'The daily work of this gene is to increase intestinal salt absorption,' said Dr. Vijay Kuchroo of Brigham and Women's Hospital. "When we put more salt in the bacterial plates, it is a In "Aha" moments, cells are turned into a group of 17 supporting T cells ".

The experiment showed that rats fed a high salt diet were more likely to develop a disease similar to MS.

Meanwhile, researchers at Yale University are also studying salt and considering human cells.

David Hafler, professor of immune biology at Yale University, told the BBC online news: "In rat models of multiple sclerosis, rats with high salt diets will have a serious illness. more important ".

"We are all really surprised to see that the change in salt levels in the diet can have such a profound effect."

People also warned about not being too worried about preliminary research results. Studies are being done in people with high blood pressure, the disease is also caused by high salts, to see if there is a link between salt and human immunodeficiency diseases.

'There is no evidence that a low salt diet can cure MS. If you already have the disease and apply a low salt diet, the situation will not be better. "

Conclusion of Professor Alastair Compston of Cambridge University.

Dr. Aviv Regev, of the Broad Institute, said: "All we can do is publish our researched knowledge to the public, we have absolutely no recommendations, there is always a gap between scientific discoveries and the application at medical facilities ".

Professor Hafler added, however, that a diet of salt will not endanger the body.

Commenting on these findings, Professor Alastair Compston, of Cambridge University, told the BBC that the research results are reliable, unexpected and very interesting.

"It seems that all the useful sciences are opening up a whole new idea that no one had ever thought of before."

He thinks that salt may have a similar effect to other factors such as smoking and sunlight, which may alter the incidence of illness.

However, he warned: There is no evidence that a low salt diet can cure MS. If you already have the disease and apply a low salt diet, the situation will not be better.

Dr. Susan Kohlhaas, head of biomedical research at MS Association, said: "This is a really interesting study and it is positive that the new research path of MS is explored in this way."

"However, it is still too early to draw firm conclusions about what these findings mean for people with MS, but we are waiting for the results of further studies."

"In the meantime, we advise people to follow government advice on maintaining a healthy and balanced diet, which includes guidelines for salt intake."