Japan successfully selected sex for artificial insemination rats

According to a reporter in Tokyo, Japanese scientists have succeeded in choosing sex for artificial fertilized mice.

In the past, the separation of X chromosomes and Y chromosome sperm was difficult because there were no functional differences between these chromosomes.

The exact rate of sex selection is up to about 80%.

These are chromosomes that determine the sex of the fetus. To solve this problem, the research team led by Professor Masayuki Shimada of Hiroshima University focused on TLR7 and TLR8 receptors, which help locate the X chromosome and are able to prevent chromatin movement. If this is stimulated.

The team mixed the chromosomes of mice in a culture medium containing catalysts, using TLR7 and TLR8 receptors to separate the X and Y chromosomes into two separate groups.

In about an hour or so, the X chromosome stops moving and settles down, while the Y chromosome, unaffected, floats upward. The separated chromosomes will be used for artificial insemination.

The exact ratio of this sex is about 80%. The results of the study were published on the online version of the biological journal PLOS Biology on August 14.