New scientific research shows: All the ways to cure alcohol in the world so far are not effective

No one really knows how to cure alcohol, that's the common conclusion that researchers draw after evaluating a series of scientific studies over time. Accordingly, there is virtually no reliable evidence that there is a cure for alcohol that works for anyone, and current methods generally produce rather poor results.

The review was conducted by researchers in the UK, and supported by the National Institutes of Health Research (NIHR), the UK's largest government-funded clinical research body. The review team analyzed 21 different clinical trials with the aim of understanding the effectiveness of a range of alcohol withdrawal modalities. These include curcumin (the main ingredient that gives turmeric its bright yellow color), red ginseng, NSAID pain relievers such as loxoprofen, probiotics, artichoke extract, pear juice, and n-acetyl-l-cysteine ​​(NAC) supplements.

There is almost no reliable evidence that there is an effective remedy for alcohol withdrawal.

Most studies have not been able to find any positive effects that other alcohol withdrawal methods might have. And even for those who noticed some significant positive effect, the researchers were simply not impressed with the quality of the data collected. None of the studies used the same method of detoxing, and all results were reproduced independently by researchers, which is essential to assessing whether a regimen is as effective as advertised. Are not_

The team also discovered a number of problems in the alcohol antidote trials. For example, eight studies did not include women. These studies also had very different designs from each other, making it difficult to compare results. Some studies have addressed the effects of food, others have not, and various alcoholic beverages were used on participants to get them into a state of intoxication. Other common anti-alcohol medications, such as acetaminophen or aspirin, have never been studied in randomized, controlled clinical trials.

"We currently have a very limited number of poor quality studies on alcohol withdrawal," said lead author Emmert Roberts, a clinical researcher at University College London.

Of the diverse methods his team is working on, three show potential, rather than being just 'psychological' like the others. They use clove extract, tolfenamic acid (an NSAID pain reliever available in the UK), and pyritinol (similar to vitamin B6). These methods are likely to be brought to clinical trials more closely, Roberts said. He also said that any future studies should adhere to more universal and well-tested criteria, including criteria for assessing symptoms of binge drinking. Such studies also need to be relatively large and include a more diverse population of participants, including women.

At the moment, there is only one method that can help you avoid the mysterious drunkenness. "The surest solution to avoiding the symptoms of binge drinking is to drink in moderation or stay away from alcohol," says Roberts. 'However, the poor quality evidence we have gathered suggests that clove extract, tolfenamic acid, and pyritinol can be highly effective in reducing symptoms of binge drinking, and that they are also safe. again'.