Self-resistant HIV cells - the most effective HIV treatment method ever

By injecting antibodies directly into cells, scientists have created a new generation of cells capable of protecting themselves from HIV.

Recently, scientists have made a breakthrough in the treatment of century disease: making cells able to resist HIV.

It is reported that antibody cells will quickly replace virus-infected cells, making the treatment effect far superior to current methods.

Specifically, researchers at The Scripps Research Institute (TSRI - California, USA) tested this method on rhinoviruses - the cause of common colds.

They used a vector called lentivirus to transfer new genes to the body's cells. They then synthesized antibodies that bind to the cell receptor that the virus needs to reach, in order to prevent the virus from invading cells and spreading the disease.

The new method is like vaccination for cells.

Cells with antibodies then die, but antibodies remain and continue to clone to protect new cells.

After success with rhinoviruses, experts continue to experiment with HIV. They realized that the HIV virus that wants to spread the disease should approach a receptor called CD4. And the rest is simple: just block these receptors, HIV cannot continue to invade cells, then they die slowly.

Researchers have partnered with investigators of the Genetic City Center of the Hope Therapy (USA) to evaluate this therapy in federal safety and efficacy tests. , before conducting a test on patients.

"This is like a vaccine at the cellular level," said Professor Richard Lerner, research director.

According to Lerner, the new method has many advantages over older therapies. In the past, antibodies floated freely in blood vessels, but now cling to cells and continue to multiply.

Antibody cells will bind to the receptors, not to reach the cell.

For the purpose of the study, experts say they will find a way to control and eliminate HIV without any other treatment.

However, Dr. Carl Dieffenbach from the UK Institute of Allergy and Infectious Diseases said the idea was problematic when developing gene therapy. He posed the question: How to know exactly which antibodies have been put into the right cell type?

"HIV has a large amount of variation, and what happens if there is a virus that does not cling to the antibodies you want? As a result, the antibodies will kill the cells, while the virus continues to grow." - Dieffenbach shares.

So, researchers are working in partnership with the City the Hope Center for Gene Therapy (USA). This is a federal regulation that assesses safety and efficacy therapy before testing on human bodies.

Great hope has, and how effective it is, begging for the future to respond.