Using sperm to transfer cancer treatment drugs

According to arXiv.org Web site, researcher Mariana Medina-Sánchez and colleagues at the Institute of Integrative Nanosciences in Dresden (Germany) have developed a unique method to deliver drugs to cancer cells.

This method is used to treat female reproductive organ cancer as well as endometriosis and endometriosis. Sperm when put into liquid environment with an active ingredient of the drug, they absorb a large amount of medicine. At the head of the sperm, the researchers placed a special iron structure. Thus, scientists can control the movement of sperm by magnetic field and regulate them to the tumor. When the sperm reaches its goal, a special mechanism will help relieve the medication.

Picture 1 of Using sperm to transfer cancer treatment drugs
When the sperm reaches its goal, a special mechanism will help relieve the medication.

When tested in laboratory conditions, Mariana Medina-Sánchez and colleagues used buffalo sperm because they resemble the most human spermatozoa and equipped them with doxorubicin - a drug commonly used in the treatment of cancer. mail, let them deliver drugs.

In the experiments, the researchers demonstrated the ability to control sperm and control sperm to deliver drugs to the right cancer cells, although the rate of sperm movement was reduced by 43% compared to normal.

In the next phase, the scientists will learn how the human body will react to the metallic nano, used in their method. In addition, scientists must find ways to adjust the dose of medication. Then they will switch to experiments with human sperm.