Zebrafish makes white mice 'arterial anti-clog drug

According to TechnologyReview , researchers at the University of California, San Diego have successfully monitored cholesterol metabolism in genetically modified zebrafish so that the whole body becomes transparent.

Researchers said it was possible to directly observe (even with the naked eye) the accumulation of LDL or bad cholesterol in the zebrafish body.

Previously, they injected zebrafish that were fed high-cholesterol diets, a drug that could reverse the accumulation of bad cholesterol, then let these "mice" have to comply with a regime. cholesterol restriction.

As a result, in the experiment, the waiting time for effects and observing the process of converting cholesterol in the organism will be faster and easier than before.

According to a team member, experimenting on zebrafish results after 10 days, while completing a similar experiment in mice requires 6 months.

The study is expected to be published in the December issue of the Journal of Clinical Investigation .