Detecting an enzyme can help prolong life

The enzyme ENAMPT has the effect of increasing the level of NAD - a substance that directly affects aging and longevity, according to tests on mice.

As well as hair loss, wrinkles and decreased mobility, latent body changes are a sign of aging. The nature of these changes is the loss of Nicotinamide Adenine Dinucleotide (NAD) - a substance that plays an important role in metabolism, blood circulation, direct impact on aging and overall life expectancy.

ENAMPT helps to increase NAD levels, increase physical activity and sleep better.

In the process of creating energy, US scientists have discovered a more important enzyme called eNAMPT . They experimented by taking the eNAMPT from the blood of small mice and putting them in the bodies of old mice. As a result, the eNAMPT increased NAD levels, increased physical activity and better sleep, leading to an increase in the life of older mice by 16%.

The old mouse group received the epilepsy had lived at least 1,029 days, equivalent to 2.8 years of human life, while the control group using salt solution survived 881 days, equivalent to 2.4 years of human life."The amount of eNAMPT is proportional to the time of live mice , " the scientists concluded.

Dr. Shin-ichiro Imai, of the research group, said the eNAMPT helps increase the circulating protein concentration in the blood, improves insulin resistance, sleep quality, mobility and cognitive function in mice old. The eNAMPT passes through the blood stream to the brain in the extracellular pockets. This fact is true for both mice and humans.

Next, the researchers will check to see if the level of ePTPT is correlated with aging-related diseases or life expectancy in humans. They believe that the body has a lot of backup systems to maintain proper NAD levels.